Results 131 to 140 of about 28,258 (264)

Regulatory T cells: the 2025 Nobel prize in physiology or medicine. [PDF]

Ups J Med Sci
Singh K.
europepmc   +1 more source

The 2022 Nobel Prize in Chemistry-sweet! [PDF]

Glycobiology, 2023
Boyce M, Malaker SA, Riley NM, Kohler JJ.   +3 more
europepmc   +1 more source

Design, synthesis and activity evaluation of tetrahydroisoquinoline‐based programmed cell death ligand 1 inhibitors

Smart Molecules, EarlyView.
Based on a 3D‐quantitative structure‐activity relationship pharmacophore model, structural optimization of Y6 yielded Y7f. Mechanistic studies revealed that Y7f acted as a programmed death receptor 1/programmed cell death ligand 1 (PD‐L1) interaction inhibitor by inducing PD‐L1 dimerization. Y7f restored T‐cell function.
Menglin Yu, Sen Cai, Yanyan Pan, Heshuang Wang, Fengwu Zhang, Aiyu Ma, Shixuan Lv, Xiuhan Guo, Shisheng Wang, Qiling Song, Chunyan Ma, Shuai Wang, Li Zhang, Jian Wang, Qingwei Meng, Yueqing Li   +15 more
wiley   +1 more source

Why Did Treg and Immune Tolerance Win Nobel Prize This Year? [PDF]

Genomics Proteomics Bioinformatics
Zheng 郑颂国 SG.
europepmc   +1 more source

The Nobel Prize awarded to pioneers of mRNA vaccines. [PDF]

Mol Ther, 2023
Herzog RW, Giangrande PH.
europepmc   +1 more source

The Allais Paradox and Upside/Downside Risk Preference: An Experimental Analysis With Probability Weighting and Chernoff Faces

Southern Economic Journal, EarlyView.
ABSTRACT The Allais Paradox is often attributed to the strong attraction of a certain option that avoids a downside risk, i.e., a small chance of a low payoff. In contrast, there is clear evidence from laboratory and field data that people are attracted to the upside risk of obtaining a relatively high payoff.
Irene Comeig, Charles Holt
wiley   +1 more source

From the Scientific Underground to the Height of Recognition: The 40th Anniversary of Rita Levi-Montalcini's Nobel Prize and the Promising Horizon in Psychiatry. [PDF]

Neurochem Res
Junkes L, Nardi AE, Clementi E.
europepmc   +1 more source

The Nobel prize in physiology and medicine - 2022. [PDF]

Struct Chem, 2023
Hagymási K.
europepmc   +1 more source

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

The Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra, Subba Rao Cheekatla, Keshaba Nanda Parida   +2 more
wiley   +1 more source

Antecedents of a Nobel prize [PDF]

Nature, 1990
openaire   +2 more sources