Results 271 to 280 of about 70,074 (346)

The human colon: Evidence for degenerative changes during aging and the physiological consequences

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 8, August 2025.
Reduced nociceptor innervation can explain diminished abdominal pain among the elderly. Degenerative changes occur within the colon wall, especially ascending colon. Mechanisms may include senescence‐like activity and inflammaging. Constipation is more likely to occur during age‐related challenges affecting functions of the bowel that now have reduced ...
Nicholas Baidoo, Gareth J. Sanger
wiley   +1 more source

Two doses of Qβ virus like particle vaccines elicit protective antibodies against heroin and fentanyl. [PDF]

open access: yesNPJ Vaccines
Romano IG   +11 more
europepmc   +1 more source

Noninvasive Compartmental Pressure Assessment With iCare in Healthy Individuals of Different Ages

open access: yesOrthopaedic Surgery, Volume 17, Issue 8, Page 2413-2421, August 2025.
The aim of the research was to compare compartmental pressure among different age groups and measurement locations. Healthy individuals who were older than 18 years were enrolled and classified into five age groups. Six measurement locations (lower, middle and upper points, 6 points) were selected to assess pressure variations in the anterior ...
Jialiang Guo   +6 more
wiley   +1 more source

The impact of topical capsaicin application on the muscle metaboreflex and microvascular responsiveness

open access: yesPhysiological Reports, Volume 13, Issue 15, August 2025.
Abstract Topical capsaicin reduces metaboreflex responses during post‐exercise circulatory arrest (PECA) in males, but its effects in females and on microvascular responsiveness in either sex remain unclear. This study hypothesized that capsaicin would reduce blood pressure during PECA in males but not females, and enhance microvascular responsiveness ...
Nikolaus D. Carpenter   +4 more
wiley   +1 more source

What is pain? [PDF]

open access: yes, 2015
Flynn, Jonathan
core  

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