Results 301 to 310 of about 70,074 (346)
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Current Opinion in Neurobiology, 1991
In recent years, progress in the treatment of pain has been strongly influenced by new insights into the mechanisms underlying pain and nociception. The following article briefly reviews some recent reports which make a significant contribution to our knowledge of the structure and function of nocisensors, the neuropeptides involved in the nociceptive ...
Bernd Heppelmann +3 more
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In recent years, progress in the treatment of pain has been strongly influenced by new insights into the mechanisms underlying pain and nociception. The following article briefly reviews some recent reports which make a significant contribution to our knowledge of the structure and function of nocisensors, the neuropeptides involved in the nociceptive ...
Bernd Heppelmann +3 more
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Cortical Modulation of Nociception
Neuroscience, 2021Nociception is the neuronal process of encoding noxious stimuli and could be modulated at peripheral, spinal, brainstem, and cortical levels. At cortical levels, several areas including the anterior cingulate cortex (ACC), prefrontal cortex (PFC), ventrolateral orbital cortex (VLO), insular cortex (IC), motor cortex (MC), and somatosensory cortices are
Abimael González-Hernández +3 more
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Advanced Materials, 2018
AbstractThe biomimetic characteristics of the memristor as an electronic synapse and neuron have inspired the advent of new information technology in the neuromorphic computing. The application of the memristors can be extended to the artificial nerves on condition of the presence of electronic receptors which can transfer the external stimuli to the ...
Yumin Kim +10 more
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AbstractThe biomimetic characteristics of the memristor as an electronic synapse and neuron have inspired the advent of new information technology in the neuromorphic computing. The application of the memristors can be extended to the artificial nerves on condition of the presence of electronic receptors which can transfer the external stimuli to the ...
Yumin Kim +10 more
openaire +2 more sources
Intraoperative Nociception Monitoring
Anesthesiology Clinics, 2021Nociception refers to the process of encoding and processing noxious stimuli. Its monitoring can have potential benefits. Under anesthesia, nociceptive signals are continuously generated to cause involuntary effects on the autonomic nervous system, reflex movement, and stress response. Most available systems depend on the identification and measurement
Girish P. Joshi +2 more
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1984
Publisher Summary This chapter describes the algesic peptides, opioid peptides, naloxone-sensitive nonopioid peptides, naloxone-insensitive peptides, and peptides with mixed effects. The chapter presents certain criteria that need to be fulfilled to demonstrate the involvement of an endogenous peptide in nociception.
Daniel E. Hernandez +3 more
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Publisher Summary This chapter describes the algesic peptides, opioid peptides, naloxone-sensitive nonopioid peptides, naloxone-insensitive peptides, and peptides with mixed effects. The chapter presents certain criteria that need to be fulfilled to demonstrate the involvement of an endogenous peptide in nociception.
Daniel E. Hernandez +3 more
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Current Drug Target -CNS & Neurological Disorders, 2004
Noxious thermal, mechanical, or chemical stimuli evoke pain through excitation of the peripheral terminals called nociceptor, and many kinds of ionotropic and metabotropic receptors are involved in this process. Capsaicin receptor TRPV1 is a nociceptor-specific ion channel that serves as the molecular target of capsaicin.
Mitsuko, Numazaki, Makoto, Tominaga
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Noxious thermal, mechanical, or chemical stimuli evoke pain through excitation of the peripheral terminals called nociceptor, and many kinds of ionotropic and metabotropic receptors are involved in this process. Capsaicin receptor TRPV1 is a nociceptor-specific ion channel that serves as the molecular target of capsaicin.
Mitsuko, Numazaki, Makoto, Tominaga
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Molecular mechanisms of nociception
Nature, 2001The sensation of pain alerts us to real or impending injury and triggers appropriate protective responses. Unfortunately, pain often outlives its usefulness as a warning system and instead becomes chronic and debilitating. This transition to a chronic phase involves changes within the spinal cord and brain, but there is also remarkable modulation where
Allan I Basbaum
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Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1985
There is evidence that the cerebral cortex is involved in the perception of pain but no specific area appears to be the ‘pain centre’. Limited knowledge exists on the cortical processing of the noxious input. The nociceptors are most likely to activate at least two different systems with different characteristics.
S. A. Andersson, B. Rydenhag
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There is evidence that the cerebral cortex is involved in the perception of pain but no specific area appears to be the ‘pain centre’. Limited knowledge exists on the cortical processing of the noxious input. The nociceptors are most likely to activate at least two different systems with different characteristics.
S. A. Andersson, B. Rydenhag
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Nociceptive pathways: anatomy and physiology of nociceptive ascending pathways
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1985In primates, the principal nociceptive pathways ascend in the anterolateral quadrant of the spinal cord. Among these, the spinothalamic tract (s.t.t.) is the best studied. Cells in Rexed’s laminae I and V project to the ventro-posterolateral (v.p.l.) thalamic nucleus.
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Prostanoids in nociception and pain
Biochemical Pharmacology, 2007Prostaglandins are lipid mediators produced by cyclooxygenases from arachidonic acid, which serve pivotal functions in inflammation and pain. Inhibition of their production is the major analgesic mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs)-but also the source of most of their unwanted effects.
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