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Nociception and pain

Current Opinion in Neurobiology, 1991
In recent years, progress in the treatment of pain has been strongly influenced by new insights into the mechanisms underlying pain and nociception. The following article briefly reviews some recent reports which make a significant contribution to our knowledge of the structure and function of nocisensors, the neuropeptides involved in the nociceptive ...
B, Heppelmann   +3 more
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Pain and Nociception in Reptiles

Veterinary Clinics of North America: Exotic Animal Practice, 2011
The ability of reptiles to "feel" pain and the significance of pain or nociception on physiologic homeostasis is an exceedingly complex question requiring integration of both physiologic and behavioral evidence. Until further information is available, it would seem most ethical for veterinarians to assume that reptiles are capable of feeling pain, and ...
openaire   +2 more sources

Prostanoids in nociception and pain

Biochemical Pharmacology, 2007
Prostaglandins are lipid mediators produced by cyclooxygenases from arachidonic acid, which serve pivotal functions in inflammation and pain. Inhibition of their production is the major analgesic mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs)-but also the source of most of their unwanted effects.
openaire   +4 more sources

Pain and Nociception

2013
Pain is a fundamental self-defense mechanism for warning against damage so that action can be taken to avoid or minimize injury. According to the International Association for the Study of Pain (IASP) pain is defined as “An unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage”
Maria P. Abbracchio, Angelo M. Reggiani
openaire   +1 more source

Pain without nociception?

European Journal of Gastroenterology & Hepatology, 2012
We describe a young woman with complete cervical spinal cord transsection, who developed significant abdominal pain, triggered by gastric distension and deep abdominal palpation. On the basis of the nature of her spinal cord injury, her brain-gut axis was limited to vagal pathways.
David J, Levinthal, Klaus, Bielefeldt
openaire   +2 more sources

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