Results 221 to 230 of about 40,810 (316)

Loss of Glutaminase 1 in Small Sensory Neurons Prevents Nerve Injury Induced Mechanical Allodynia: Insights From Conditional Knockout Mice. [PDF]

Eur J Pain
Martínez-Padilla A, Márquez J, Huerta MÁ, Roza C, Cisneros E.   +4 more
europepmc   +1 more source

Comparative Effectiveness and Safety of Adalimumab, Secukinumab, and Upadacitinib in Psoriatic Arthritis: A Prospective Cohort Study Based on PARWCH Cohort

The Journal of Dermatology, Volume 52, Issue 10, Page 1527-1535, October 2025.
ABSTRACT Psoriatic arthritis (PsA) is a chronic inflammatory disease, with prevalence among psoriasis patients ranging from 6% to 42% across populations. Although targeted therapies such as adalimumab (ADA), secukinumab (SEC), and upadacitinib (UPA) have demonstrated efficacy in randomized controlled trials, real‐world head‐to‐head comparisons remain ...
Yiyi Wang, Jingya Gao, Furong Li, Luyuan Li, Yue Xiao, Hongxiang Hu, Xiya Peng, Min Yang, Dan Hao, Wei Yan, Dengmei Xia, Wei Li   +11 more
wiley   +1 more source

Truncated TrkB: The predominant TrkB isoform in nociceptors. [PDF]

J Pain
Merlo J, Chang FM, Tran M, Alfaro J, Ibrahim T, Wu P, Ruparel S.   +6 more
europepmc   +1 more source

Pain Perception and Modulation: Fundamental Neurobiology and Recent Advances

European Journal of Neuroscience, Volume 62, Issue 8, October 2025.
Chronic pain is a major burden with variable treatment responses reflecting complex biopsychosocial and neurobiological factors. This narrative review synthesizes evidence on neural structures, circuits, and mediators involved in pain perception and modulation.
Willem W. J. van Strien, Markus W. Hollmann   +1 more
wiley   +1 more source

A distributed coding logic for thermosensation and inflammatory pain. [PDF]

Nature
Ghitani N, von Buchholtz LJ, MacDonald DI, Falgairolle M, Nguyen MQ, Licholai JA, Ryba NJP, Chesler AT.   +7 more
europepmc   +1 more source

Trigeminal Nociceptors Express TLR-4 and CD14: a Mechanism for Pain due to Infection [PDF]

, 2006
R. Wadachi, Kenneth Hargreaves
openalex   +1 more source

The Spectrum of Headaches in Moyamoya Angiopathy: From Mechanisms to Management Strategies—A Consensus Review From the NEUROVASC Working Group

European Journal of Neurology, Volume 32, Issue 10, October 2025.
This article explores headache as a common yet underrecognized symptom of Moyamoya angiopathy (MMA), affecting up to 75% of patients. It reviews the potential pathophysiological mechanisms, including impaired autoregulation and microvascular ischemia, and discusses current and emerging treatment strategies, such as revascularization surgery and CGRP ...
Nicola Rifino, Anne Hege Aamodt, Markus Wiedmann, Markus Kramer, Jana Becker, Stéphanie Guey, Francesco Acerbi, Dominique Herve, Anna Bersano   +8 more
wiley   +1 more source

Comprehensive Mechanisms and Non-Invasive Treatment for Complex Regional Pain Syndrome: A Narrative Review. [PDF]

J Pain Res
Doan HN, Chang MC.
europepmc   +1 more source

Glial Cell Line-Derived Neurotrophic Factor Expression in Skin Alters the Mechanical Sensitivity of Cutaneous Nociceptors [PDF]

, 2006
Kathryn M. Albers, C. Jeffrey Woodbury, Amy M. Ritter, Brian M. Davis, H. Richard Koerber   +4 more
openalex   +1 more source

Symptom correlation and spatial distribution of inflammatory mediators in pulpitis—A preliminary study

International Endodontic Journal, Volume 58, Issue 10, Page 1565-1581, October 2025.
Abstract Aim To evaluate the association of inflammatory mediators with clinical signs and symptoms and their spatial distribution in teeth with pulpitis. Methodology Fifty permanent teeth from adults with clinical diagnoses of normal pulp (n = 17), reversible pulpitis (n = 13) and symptomatic/asymptomatic irreversible pulpitis (n = 20), were recruited.
Ai Leen Shu Jen Loo, Rong Cen, Junwen Wang, Zhaoming Wu, Henry Fergus Duncan, Angeline Hui Cheng Lee, Chengfei Zhang   +6 more
wiley   +1 more source