Results 221 to 230 of about 49,496 (354)

A paradigm shift in analgesic discovery: from rodent to human models. [PDF]

Korean J Pain
Han RT.
europepmc   +1 more source

Abnormal Resting‐State Functional Connectivity Between the Dorsal Anterior Cingulate Cortex and the Limbic System Contributes to Pain and Emotion Regulation Impairment in Fibromyalgia Patients

International Journal of Rheumatic Diseases, Volume 29, Issue 1, January 2026.
ABSTRACT Objectives The subdivisions of the anterior cingulate cortex (ACC) are involved in distinct functions in the processing of chronic pain and regulation of emotions. However, the specific impact of each ACC subdivision on fibromyalgia (FM) remains unclear.
Yu Wang, Yixin Zhou, Aihui Liu, Chengliang Mao, Shinan Li, Shan Huang, Xingyi Zhu, Hongyang Jiang, Zhenhua Ying   +8 more
wiley   +1 more source

The neuroimmune axis and chronic pain disorders. [PDF]

iScience
Feenstra RA, den Dunnen WFA, Laman JD.
europepmc   +1 more source

Single‐Nuclei Resolution of Intermuscular Adipose Tissue Indicates an Inflammation‐Associated Cellular Profile in Individuals With Knee Osteoarthritis: Findings From the SOMMA KOA Ancillary Study

Aging Cell, Volume 25, Issue 1, January 2026.
Interrogation of the cellular and transcriptional profile of IMAT in individuals with KOA reveals a pro‐inflammatory phenotype. ABSTRACT Individuals with knee osteoarthritis (KOA) have skeletal muscle changes around the knee joint including reduced quadricep muscle mass and increased intermuscular adipose tissue (IMAT).
Line O. Elingaard‐Larsen, Katie L. Whytock, Adeline Divoux, Cheehoon Ahn, Giovanna Distefano, Bret H. Goodpaster, Paul M. Coen, Jamie N. Justice, Erin E. Kershaw, Nancy E. Lane, Lauren M. Sparks   +10 more
wiley   +1 more source

Co-cultured sensory neuron classification using extracellular electrophysiology and machine learning approaches for enhancing analgesic screening. [PDF]

J Neural Eng
Somers A, Black BJ.
europepmc   +1 more source

Metabolic tuning facilitates nociceptor resilience to excitotoxicity [PDF]

Lin Yuan, Navdeep S. Chandel, David Julius   +2 more
openalex   +1 more source

NGF-mediated photoablation of nociceptors reduces pain behavior in mice [PDF]

, 2019
Linda Nocchi, Carla Portulano, Federica Franciosa, B Doleshall, Mirela Panea, Nainika Roy, Mariano Maffei, Alessandra Gargano, Emerald Perlas, PA Heppenstall   +9 more
openalex   +1 more source

Piezo2 in Mechanosensory Biology: From Physiological Homeostasis to Disease‐Promoting Mechanisms

Cell Proliferation, Volume 59, Issue 1, January 2026.
Piezo2 channels are essential mechanotransducers regulating touch, proprioception and visceral mechanosensation across physiological systems, emerging as therapeutic targets for pathological mechanical hypersensitivity and neurogenic disorders. ABSTRACT Piezo2, a mechanically activated ion channel, serves as the key molecular transducer for touch ...
Zhebin Cheng, Zuping Wu, Mengjie Wu, Liang Xie, Qianming Chen   +4 more
wiley   +1 more source

TRPV1 and TRPV1-Expressing Nociceptors Mediate Orofacial Pain Behaviors in a Mouse Model of Orthodontic Tooth Movement [PDF]

, 2019
Sheng Wang, Martin Kim, Zayd Ali, Katherine Ong, Eung‐Kwon Pae, Man‐Kyo Chung   +5 more
openalex   +1 more source

Acute severe lameness associated with proliferative bone on the dorsal middle phalanx (19 cases)

Equine Veterinary Education, Volume 38, Issue 1, Page 26-36, January 2026.
Summary Background Injury resulting in proliferative new bone formation on the dorsal aspect of the middle phalanx (P2) has been recognised by equine veterinarians and is generally referred to as capsulitis. However, no retrospective case series has been published on the condition. Objectives To describe the clinical features, treatment, and outcome of
J. G. Fowlie, H. D. O'Neill, F. A. Nickels, S. Mattson   +3 more
wiley   +1 more source