Results 111 to 120 of about 654,548 (335)
Radiotherapy and Oncology, 2019 PURPOSE/OBJECTIVE(S) To investigate the patterns of nodal failure in patients enrolled in the international multicentre EMBRACE study. MATERIALS/METHODS Nodal disease at diagnosis (N-, N+) and nodal failure were analysed per region (NF) (pelvic ...
C. Nomden +17 more
semanticscholar +1 more source
, 2017 Topological nodal-line semimetals are characterized by one-dimensional lines of band crossing in the Brillouin zone. In contrast to nodal points, nodal lines can be in topologically nontrivial configurations. In this Rapid Communication, we introduce the
Ren Bi, Zhongbo Yan, Ling Lu, Zhong Wang
semanticscholar +1 more source
Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis
Advanced Science, EarlyView.Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason +12 more
wiley +1 more source
Pathology and Oncology ResearchAdvanced melanoma is considered the most aggressive and deadly form of skin cancer whose incidence has been rising over the past three decades. In the absence of treatment, the median overall survival for advanced-stage metastatic disease is less than 6 ...
Philippe D. Gascard +7 more
doaj +1 more source
Advanced Science, EarlyView.Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji +10 more
wiley +1 more source
Complex Land Systems: the Need for Long Time Perspectives to Assess their Future
Ecology and Society, 2010 The growing awareness about the need to anticipate the future of land systems focuses on how well we understand the interactions between society and environmental processes within a complexity framework.
John A. Dearing +4 more
doaj +1 more source
Frontiers in Chemistry, 2020 In recent years, topological semimetals/metals, including nodal point, nodal line, and nodal surface semimetals/metals, have been studied extensively because of their potential applications in spintronics and quantum computers.
Heju Xu, Hailong Xi, Yong-Chun Gao
doaj +1 more source
Nodal inequalities on surfaces
, 2006 Given a Laplace eigenfunction on a surface, we study the distribution of its extrema on the nodal domains. It is classically known that the absolute value of the eigenfunction is asymptotically bounded by the 4-th root of the eigenvalue.
Chavel +4 more
core +3 more sources
SpatialESD: Spatial Ensemble Domain Detection in Spatial Transcriptomics
Advanced Science, EarlyView.ABSTRACT Spatial transcriptomics (ST) measures gene expression while preserving spatial context within tissues. One of the key tasks in ST analysis is spatial domain detection, which remains challenging due to the complex structure of ST data and the varying performance of individual clustering methods. To address this, we propose SpatialESD, a Spatial
Hongyan Cao +11 more
wiley +1 more source
Lifshitz Transition in Correlated Topological Semimetals
Advanced Science, EarlyView.Theoretical calculations reveal that in YPtBi and GdPtBi, strong electronic correlations shift topological Dirac nodes away from the Fermi level by forming large hole pockets. This effect is sensitive to temperature and arises from interactions among 4d or 4f electrons, offering insights into Fermi surface engineering in quantum materials.
Byungkyun Kang +4 more
wiley +1 more source