Results 151 to 160 of about 12,833 (259)

An optogenetic toolkit for robust activation of FGF, BMP, & Nodal signaling in zebrafish. [PDF]

Dev Biol
Iannucci LE, Maria Thomas VS, Anderson WK, Murphy MR, Donahue CET, Campbell CE, Monaghan MT, Saul AJ, Rogers KW.   +8 more
europepmc   +1 more source

Clinical Outcomes of the POPCORN Study: Pharmacodynamics of Pre‐Operative PD1 CheckpOint Blockade and Receptor Activator of NF‐κB Ligand (RANKL) Inhibition in Non‐Small Cell Lung Cancer (NSCLC)—A Phase 1B/2 Trial

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Expanding on the growing evidence for neoadjuvant immunotherapy in resectable non‐small cell lung cancer, this study explored neoadjuvant nivolumab ± denosumab. Two of the 10 treated patients achieved a pathological complete response. CD8 T‐cell infiltration correlated with pathological response, warranting ongoing translational research to understand ...
Elizabeth Ahern, Cassie Turner, Rishendran Naidoo, David Godbolt, Amy Ives, Kirsten Popplewell, Zarnie Lwin, Sally Pearson, Kimberley Nelson, Jason Madore, William C Dougall, Brett G. M. Hughes   +11 more
wiley   +1 more source

A New Remote Classroom Approach to Contouring Training for Pelvic Malignancies in Low- to Middle-Income Asian Countries. [PDF]

Cureus
Liu Y, Carlson C, Prajogi GB, Jhingran A, Holliday E, Paly J, Longo J, Puckett LL, Zaorsky NG, Sarria G, Castaneda SA, Li BC.   +11 more
europepmc   +1 more source

Impact of RAS/RAF Mutations on Metastatic Treatment Response Following Total Neoadjuvant Therapy in Patients With Stage IV Rectal Cancer

Asia-Pacific Journal of Clinical Oncology, EarlyView.
There is limited understanding of the impact of underlying RAS/RAF mutational status on total neoadjuvant therapy metastatic tumor response rates in curative Stage IV rectal cancer patients. Complete metastatic tumor response to TNT was demonstrated in half as many mRAS as wtRAS patients and disease progression was higher in patients harboring RAS ...
Tracy R. Fitzsimmons, Z. Bunjo, E. L. Neo, A. Badiei, M. Penniment, S. Selva‐Nayagam, A. Ruszkiewicz, J. Wong, T. Sammour   +8 more
wiley   +1 more source

Beyond the T: Volumetric MRI Predicts Lymphatic Spread in Oral Squamous Cell Carcinoma. [PDF]

Cancers (Basel)
Thoenissen P, Giardino D, Yel I, Vogl TJ, Mahmoudi S, Nica AI, Diers J, Fleischmann M, Issing C, Sader R, Girometti R, D'angelo T, Booz C, Ghanaati S.   +13 more
europepmc   +1 more source

Sentinel Lymph Node Biopsy in Clinically Node‐Negative Merkel Cell Carcinoma: An Update of the Westmead Hospital Experience

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine malignancy with a high risk of nodal metastasis. Sentinel lymph node biopsy (SLNB) is used to stage clinically node‐negative disease and to guide adjuvant therapy decisions.
Julie Ahn, Julie R. Howle, Michael J. Veness   +2 more
wiley   +1 more source

Intrafractional Motion and Margin Assessment for Cone Beam Computed Tomography Guided Online Adaptive Radiation Therapy in Head and Neck Cancer. [PDF]

Adv Radiat Oncol
Liao CY, Domal S, Yarlagadda P, Tomagan JM, Parsons D, Wang J, Avkshtol V, Jiang S, Moon D, Sher D, Lin MH.   +10 more
europepmc   +1 more source

Rescaling the Developmental State: Competitive Shrinkage Governance and the Spatial Restructuring of Higher Education in South Korea

Asia Pacific Viewpoint, EarlyView.
ABSTRACT Against the backdrop of sustained demographic contraction across the Asia‐Pacific, the developmental state (DS) paradigm, long premised on growth, faces profound challenges. While existing research on shrinking regions focuses on urban planning, little attention has been paid to how the state restructures its spatial power under contraction ...
Li Mingfeng
wiley   +1 more source

Live imaging and functional characterization of the avian hypoblast redefine the mechanisms of primitive streak induction. [PDF]

Nat Commun
Villedieu A, Alegria-Prévot O, Phan C, Ieda Y, Corson F, Gros J.   +5 more
europepmc   +1 more source

Clinical outcomes of the chemo‐free approach in relapsed/refractory follicular lymphoma: A network meta‐analysis

British Journal of Haematology, EarlyView.
Graphical overview of the network meta‐analysis (NMA) evaluating chemo‐free approaches for relapsed/refractory follicular lymphoma (R/R FL). Epcoritamab plus rituximab (R2) achieved the highest cumulative ranking probability (SUCRA) across efficacy end‐points but increases the risk of predictable toxicity over anti‐CD20 monotherapy.
Daniele Caracciolo, Maria Rita Lombardo, Gianluca Reitano, Cristina Napoli, Lucia Fiorillo, Chiara Callerame, Mario Garritano, Alessio Bulotta, Maha Munir, Giulia Pensabene, Emiliano Barbieri, Alberto Bavieri, Pierfrancesco Tassone, Pierosandro Tagliaferri, Stefano Luminari   +14 more
wiley   +1 more source