Results 51 to 60 of about 124,528 (252)
Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun +27 more
wiley +1 more source
Tropical refined curve counting via motivic integration
We propose a geometric interpretation of Block and G\"ottsche's refined tropical curve counting invariants in terms of virtual $\chi_{-y}$-specializations of motivic measures of semialgebraic sets in relative Hilbert schemes.
Nicaise, Johannes +2 more
core +1 more source
Transcriptional integration of Wnt and Nodal pathways in establishment of the Spemann organizer
Signaling inputs from multiple pathways are essential for the establishment of distinct cell and tissue types in the embryo. Therefore, multiple signals must be integrated to activate gene expression and confer cell fate, but little is known about how this occurs at the level of target gene promoters.
Reid, Christine D. +3 more
openaire +2 more sources
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li +10 more
wiley +1 more source
Dispersion Anomalies in Cuprate Superconductors
We argue that the shape of the dispersion along the nodal and antinodal directions in the cuprates can be understood as a consequence of the interaction of the electrons with collective spin excitations.
A. V. Chubukov +3 more
core +1 more source
A Note on the Integrality Gap in the Nodal Interdiction Problem
In the maximum flow network interdiction problem, an attacker attempts to minimize the maximum flow by interdicting flow on the arcs of network. In this paper, our focus is on the nodal interdiction for network instead of the arc interdiction. Two path inequalities for the node-only interdiction problem are represented.
openaire +2 more sources
First‐principles calculations reveal that monolayer In2O${\rm In}_2{\rm O}$ hosts type‐II Dirac fermions near the Fermi level, which split into Weyl points under spin‐orbit coupling. The material exhibits negative and giant magnetoresistance, a pronounced spin Hall effect, and phonon‐mediated superconductivity at 1.5 K, establishing it as a unique ...
Qing‐Bo Liu +6 more
wiley +1 more source
Renewable Electric Energy Integration: Quantifying the Value of Design of Markets for International Transmission Capacity [PDF]
Integrating large quantities of supply-driven renewable electricity generation remains a political and operational challenge. One of the main obstacles in Europe to installing at least 200 GWs of power from variable renewable sources is how to deal with ...
Benjamin Hobbs +13 more
core
The Ground State of the Pseudogap in Cuprate Superconductors
We present studies of the electronic structure of La2-xBaxCuO4, a system where the superconductivity is strongly suppressed as static spin and charge orders or "stripes" develop near the doping level of x=1/8.
Davis, J. C. +4 more
core +1 more source
This study reports a novel rationally‐designed optical nanoprobe based on dumbbell‐shaped mesoporous silica‐coated gold nanorods, loaded with rare‐earth oxides, photosensitizers, and tumor‐targeted peptides, enabling plasmonic‐enhanced multimodal imaging and PTT‐PDT synergy.
Baikang Zhuang +12 more
wiley +1 more source

