ABSTRACT Background Postoperative radiotherapy is the standard treatment for locally advanced oral squamous cell carcinoma (OSCC); however, the indication for neck irradiation (NI) in pN0 patients remains debatable. We evaluated whether the omission of NI compromises outcomes in pT3–T4 pN0 patients treated with adequate neck dissection (ND).
Mathilde Mirallié +9 more
wiley +1 more source
Differentiating pulmonary sarcoidosis from mediastinal lymph node metastasis via conventional computed tomography features and quantitative imaging parameters: a retrospective study. [PDF]
Liu Y, Xu N, Liu S, Zhao L.
europepmc +1 more source
ABSTRACT Background Neoadjuvant chemoimmunotherapy is being explored in locally advanced head and neck squamous cell carcinoma (HNSCC), yet the spatial patterns of pathologic response and clinical implications remain poorly characterized. Methods A 79‐year‐old female with recurrent left oral tongue SCC (PD‐L122C3 Combined Positive Score 90) who ...
Andreja Radevic +9 more
wiley +1 more source
Utilization of invasive mediastinal nodal staging and prevalence of occult nodal disease in patients with synchronous primary lung cancers. [PDF]
Zhou N +17 more
europepmc +1 more source
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) lacks an established screening program, and most cases are diagnosed at advanced stages. Multi‐cancer early detection (MCED) blood‐based assays represent a promising approach, yet real‐world clinical experience with MCED‐identified HNSCC remains limited.
Abhinav Talwar +3 more
wiley +1 more source
Multimodal brain network disruption and structural-functional decoupling in overt hypothyroidism. [PDF]
Yu H +12 more
europepmc +1 more source
ABSTRACT Background Locoregional recurrence remains a clinically relevant problem in oral squamous cell carcinoma (OSCC). Whether local, ipsilateral nodal, and contralateral nodal failure represent distinct disease processes with different clinicopathological associations has not been systematically evaluated.
Jannik Ketschau +9 more
wiley +1 more source
Maintaining genetic stability in sweet potato: epigenetic insights into propagation and drought tolerance. [PDF]
Dhungana A +6 more
europepmc +1 more source
A Discharge Summary Prompt Reduces Postoperative Radiotherapy Delay in Head and Neck Cancer Patients
ABSTRACT Background Delays in postoperative radiotherapy (PORT) beyond 6 weeks are associated with worse outcomes in head and neck cancer (HNC). This study evaluated whether a discharge summary prompt could reduce PORT delay. Methods A retrospective review of patients from 2018 to 2023 was used as a pre‐intervention baseline.
Andreja Radevic +10 more
wiley +1 more source
Rethinking Invasive Mediastinal Staging in the Era of Neoadjuvant Immune-Checkpoint Inhibitors. [PDF]
Silva SB +5 more
europepmc +1 more source

