Results 81 to 90 of about 5,716,538 (321)

Ras/Raf-1/MAPK pathway mediates response to tamoxifen but not chemotherapy in breast cancer patients [PDF]

open access: yes, 2009
<b>Purpose</b>: The expression and activation of the Ras/Raf-1/mitogen-activated protein kinase (MAPK) pathway plays an important role in the development and progression of cancer, and may influence response to treatments such as tamoxifen ...
Bartlett, J.M.S.   +7 more
core   +1 more source

Nodal-dependent mesendoderm specification requires the combinatorial activities of FoxH1 and Eomesodermin.

open access: yesPLoS Genetics, 2011
Vertebrate mesendoderm specification requires the Nodal signaling pathway and its transcriptional effector FoxH1. However, loss of FoxH1 in several species does not reliably cause the full range of loss-of-Nodal phenotypes, indicating that Nodal signals ...
Christopher E Slagle   +2 more
doaj   +1 more source

Gene expression analysis of bovine embryonic disc, trophoblast and parietal hypoblast at the start of gastrulation [PDF]

open access: yes, 2017
In cattle early gastrulation-stage embryos (Stage 5), four tissues can be discerned: (i) the top layer of the embryonic disc consisting of embryonic ectoderm (EmE); (ii) the bottom layer of the disc consisting of mesoderm, endoderm and visceral hypoblast
Berg, D   +3 more
core   +2 more sources

Distinct modes of floor plate induction in the chick embryo [PDF]

open access: yes, 2003
To begin to reconcile models of floor plate formation in the vertebrate neural tube, we have performed experiments aimed at understanding the development of the early floor plate in the chick embryo. Using real-time analyses of cell behaviour, we provide
Fraser, Scott   +4 more
core   +1 more source

Integration of Nodal and BMP Signaling by Mutual Signaling Effector Antagonism

open access: yesCell Reports, 2020
Summary: Opposing sources of bone morphogenetic protein (BMP) and Nodal signaling molecules are sufficient to induce the formation of a full axis in zebrafish embryos.
Gary Huiming Soh   +2 more
doaj  

Epstein-Barr virus-associated primary nodal T/NK-cell lymphoma shows a distinct molecular signature and copy number changes

open access: yesHaematologica, 2018
The molecular biology of primary nodal T- and NK-cell lymphoma and its relationship with extranodal NK/T-cell lymphoma, nasal type is poorly understood. In this study, we assessed the relationship between nodal and extranodal Epstein-Barr virus-positive ...
Siok-Bian Ng   +21 more
doaj   +1 more source

Xnrs and activin regulate distinct genes during Xenopus development: activin regulates cell division. [PDF]

open access: yesPLoS ONE, 2007
BACKGROUND:The mesoderm of the amphibian embryo is formed through an inductive interaction in which vegetal cells of the blastula-staged embryo act on overlying equatorial cells.
Joana M Ramis   +2 more
doaj   +1 more source

Increased Glypican-3 immunostaining is associated with longer survival outcomes in colorectal carcinoma

open access: yesPolish Journal of Pathology, 2022
Glypicans (GPC) are involved in the developmental morphogenesis and regulatory processes of cell signalling. Abnormal expression has been observed in different cancer types.
Jaudah Al-Maghrabi   +5 more
doaj   +1 more source

Activation of Akt at T308 and S473 in alcohol, tobacco and HPV-induced HNSCC:is there evidence to support a prognostic or diagnostic role? [PDF]

open access: yes, 2014
BACKGROUND: Tobacco, alcohol and HPV infection are associated with increased risk of HNSCC. However, little is known about the underlying signaling events influencing risk.
Cochrane, Lynda   +4 more
core   +2 more sources

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