Results 51 to 60 of about 2,499,483 (247)

EBSL: supporting deleted node label reuse in XML [PDF]

, 2010
Recently, there has been much research into the specification of dynamic labeling schemes supporting XML updates. The primary design goal of any dynamic labeling scheme is to limit the growth rate in node label size, and consequently increase query ...
O\u27Connor, Martin F., Roantree, Mark, Mark Roantree, O'Connor, Martin F., Martin F. O’Connor   +4 more
core   +2 more sources

SETTA: Parameter-Free Test-Time Adaptation for Graph Neural Networks via Spectral-Energy-Guided Semantic Refinement

Big Data and Cognitive Computing
Node classification is a central graph data mining task, yet repeated message passing can over-smooth representations and degrade frozen graph neural network (GNN) predictions after deployment.
Dongyang Yu, Xia Cui, Rong Xiao
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

SNOC: Streaming Network Node Classification

, 2014
© 2014 IEEE. Many real-world networks are featured with dynamic changes, such as new nodes and edges, and modification of the node content. Because changes are continuously introduced to the network in a streaming fashion, we refer to such dynamic ...
Pei, J, Guo, T, Xingquan Zhu, Zhang, C, Chengqi Zhang, Jian Pei, Zhu, X, Ting Guo   +7 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

GRE²-MDCL: Graph Representation Embedding Enhanced via Multidimensional Contrastive Learning

IEEE Access
Graph representation learning aims to preserve graph topology when mapping nodes to vector representations, enabling downstream tasks like node classification and community detection.
Quanjun Li, Weixuan Li, Xiya Zheng, Junhua Zhou, Wenming Zhong, Xuhang Chen, Chao Long   +6 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Identifying Key Nodes for the Influence Spread Using a Machine Learning Approach

Entropy
The identification of key nodes in complex networks is an important topic in many network science areas. It is vital to a variety of real-world applications, including viral marketing, epidemic spreading and influence maximization.
Mateusz Stolarski, Adam Piróg, Piotr Bródka   +2 more
doaj   +1 more source