Results 61 to 70 of about 263,942 (258)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

GRE²-MDCL: Graph Representation Embedding Enhanced via Multidimensional Contrastive Learning

IEEE Access
Graph representation learning aims to preserve graph topology when mapping nodes to vector representations, enabling downstream tasks like node classification and community detection.
Quanjun Li, Weixuan Li, Xiya Zheng, Junhua Zhou, Wenming Zhong, Xuhang Chen, Chao Long   +6 more
doaj   +1 more source

Improving Node Classification Accuracy in Graph Neural Networks Using PageRank as an Additional Node Feature [PDF]

پژوهش‌های نظری و کاربردی هوش ماشینی
This paper presents a simple yet effective approach to enhance the performance of Graph Neural Networks (GNNs) in node classification tasks. The proposed method involves incorporating the PageRank score—a global centrality metric—into node feature ...
Hossein Hosseini, Mehdi Naghavi
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Identifying Key Nodes for the Influence Spread Using a Machine Learning Approach

Entropy
The identification of key nodes in complex networks is an important topic in many network science areas. It is vital to a variety of real-world applications, including viral marketing, epidemic spreading and influence maximization.
Mateusz Stolarski, Adam Piróg, Piotr Bródka   +2 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

A Process for the Evaluation of Node Embedding Methods in the Context of Node Classification

CoRR, 2020
Node embedding methods find latent lower-dimensional representations which are used as features in machine learning models. In the last few years, these methods have become extremely popular as a replacement for manual feature engineering. Since authors use various approaches for the evaluation of node embedding methods, existing studies can rarely be ...
Christoph Martin, Meike Riebeling
openaire   +2 more sources

Review of Node Classification Methods Based on Graph Convolutional Neural Networks [PDF]

Jisuanji kexue
Node classification is one of the important research tasks in graph field.In recent years,with the continuous deepening of research on graph convolutional neural network,significant progress has been made in the research and application of node ...
ZHANG Liying, SUN Haihang, SUN Yufa , SHI Bingbo
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source