Results 121 to 130 of about 51,241 (256)
Interdisciplinary Medicine, EarlyView.This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma +6 more
wiley +1 more source
CTLA-4: a negative regulator of autoimmune disease. [PDF]
, 1996 CTLA-4, a CD28 homologue expressed on activated T cells, binds with high affinity to the CD28 ligands, B7-1 (CD80) and B7-2 (CD86). This study was designed to examine the role of CTLA-4 in regulating autoimmune disease.
Bluestone, JA +4 more
core
NK Cells in the Lymph Nodes and Their Role in Anti-Tumour Immunity [PDF]
BiomedicinesThe lymph nodes are vital to enable adaptive immune responses to infection. Natural killer (NK) cells are cytotoxic lymphocytes that directly kill cancer cells and modulate the activation of other immune cells during anti-tumour immune response.
Lara V. Graham +2 more
openaire +4 more sources
Interdiction Models and Heuristics for Graph Propagation
Networks, EarlyView.ABSTRACT Given a graph G=(V,E)$$ G=\left(V,E\right) $$ and a set S⊂V$$ S\subset V $$ of activated/infected nodes, we consider the problem of determining the set of c$$ c $$ nodes that minimizes the network propagation on the subgraph that results from the removal of those c$$ c $$ nodes. To measure network propagation, we assume that a node i$$ i $$ is
Agostinho Agra, José Maria Samuco
wiley +1 more source
Rheumatology &Autoimmunity, EarlyView.Schematic Summary of Circadian Dysregulation in Arthritic Joints. This graphical abstract illustrates the key circadian disruptions observed in the collagen‑induced arthritis (CIA) model. The diagram depicts three main findings: (1) Nocturnal elevations in pro‑inflammatory cytokines (TNF‑α, IL‑6, IL‑17, IL‑1β, MIF) and bone‑destructive factors (DKK‑1 ...
Xiaogang Zhang +7 more
wiley +1 more source
Biochemistry and Biophysics ReportsC–C chemokine receptor type 7 (CCR7) is a member of the G protein-coupled receptor family and functions as a lymph node-homing receptor for immune cells. Upon ligand binding, CCR7 promotes the migration of immune cells to secondary lymphoid organs.
Hiroyuki Satofuka +10 more
doaj +1 more source
Wildlife Letters, EarlyView.The Amur tiger, an endangered flagship species mainly found in the Russia Far East and Northeastern China, holds immense biological importance, and has been listed under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES).
Wei Xie +15 more
wiley +1 more source
FORECASTING MEASLES COVERAGE USING ARTIFICIAL NEURAL NETWORK
Journal of University Medical & Dental College, 2018 : OBJECTIVES: To propose the forecasting model for monthly measles infant immunization coverage a significant concern in disease management and control.
Jamal Abdul Nasir +2 more
doaj
STAR ProtocolsSummary: Lymph nodes orchestrate adaptive immune responses, with germinal centers enabling affinity maturation and plasma cell formation. Here, we present a protocol for rapid, high-resolution, multicolor 3D imaging of whole immunized mouse lymph nodes ...
Victoire Boulat +5 more
doaj +1 more source
Effects of intermittent fasting on experimental autoimune encephalomyelitis in C57BL/6 mice [PDF]
, 2016 Several religions recommend periods of fasting. One of the most frequently asked questions of MS patients before the holy month of Ramadan is weather fasting might have an unfavorable effect on their disease course.
Alizadeh, A. +5 more
core +1 more source