Results 191 to 200 of about 2,301,764 (289)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

The value of positron emission tomography scan in predicting pathologic response of non-small cell lung cancer managed by neoadjuvant chemo-immunotherapy. [PDF]

J Thorac Dis
Chriqui LE, Zaher M, Abdelnour-Berchtold E, Bouchaab H, Mederos N, Berezowska S, Gonzalez M, Zellweger M, Peters S, Krueger T, Schaefer N, Perentes JY.   +11 more
europepmc   +1 more source

Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes.

Immunity, 2006
Marc Bajénoff, J. Egen, Lily Y. Koo, J. Laugier, Frédéric Brau, Nicolas Glaichenhaus, Ronald N. Germain   +6 more
semanticscholar   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Golden‐Ratio–Guided Aperiodic Architected Metamaterials with Simultaneously Enhanced Strength and Toughness

Advanced Functional Materials, EarlyView.
Guided by the golden ratio, a class of aperiodic architected metamaterials is introduced to address the intrinsic trade‐off between strength and toughness. By unifying local geometric heterogeneity with global order, the golden‐ratio‐guided aperiodic architecture promotes spatial delocalization of damage tolerence regions, leading to more tortuous ...
Junjie Deng, Xinxin Wang, Ruochao Zhao, Zhendong Li, Kai Liu, Ke Yuan, Jia An, Xinwei Li, Chee Kai Chua, Zhonggang Wang   +9 more
wiley   +1 more source

Food addiction in behavioral addictions: a network approach. [PDF]

Front Psychol
Gaspar-Pérez A, Granero R, Fernández-Aranda F, Rosinska M, Sabariegos-Campos N, Artero C, Ruiz-Torras S, Gearhardt AN, Demetrovics Z, Czakó A, Guàrdia-Olmos J, Jiménez-Murcia S.   +11 more
europepmc   +1 more source

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

Protocol for precision cutting and short-term culture of lymph node tissue slices for modeling of innate immune responses ex vivo. [PDF]

STAR Protoc
Fergusson JR, Coles M, Dendrou CA, Milicic A.   +3 more
europepmc   +1 more source

Tailoring Microstructure in Copper‐Based Conductive Metal–Organic Frameworks for Enhanced Chemiresistive Sensing and Uptake of Sulfur Dioxide

Advanced Functional Materials, EarlyView.
Precursor‐ and solvent‐mediated synthesis yields four Cu3(HHTP)2 morphologies with distinct physicochemical, sorption, and sensing properties toward SO2. Uptake capacities correlate with BET surface area, while sensing performance scales with particle aspect ratio.
Patrick Damacet, Zhuoran Zhong, Elí Sánchez‐González, Camille L. Slagle, Ilich A. Ibarra, Katherine A. Mirica   +5 more
wiley   +1 more source

Dynamics and energy encoding of a star-like neuron network composed of the Wang-Zhang model induced by compressing a sphere into a fingertip. [PDF]

Cogn Neurodyn
Shi X, Xu W, Zhuang L, Meng F, Jiang H, Wang Z.   +5 more
europepmc   +1 more source