Results 41 to 50 of about 1,319,186 (317)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Characterisation of antigen-presenting cells in the murine female reproductive tract and its draining lymph nodes [PDF]

open access: yes, 2011
Despite the global burden of sexually transmitted diseases, the immunology of the female reproductive tract is poorly understood. An understanding of how the distribution of antigen presenting cells in the tissue and cross talk between cell types both ...
Roche, Rebecca
core  

Detecting Traffic Conditions Model Based On Clustering Nodes Situations In VANET [PDF]

open access: yes, 2015
In the last decade, cooperative vehicular network has been one of the most studied areas for developing the intelligent transportation systems (ITS).
Peytchev, E   +3 more
core   +1 more source

Relaxation Mechanisms, Structure and Properties of Semi-Coherent Interfaces

open access: yesMetals, 2015
In this work, using the Cu–Ni (111) semi-coherent interface as a model system, we combine atomistic simulations and defect theory to reveal the relaxation mechanisms, structure, and properties of semi-coherent interfaces.
Shuai Shao, Jian Wang
doaj   +1 more source

BlockChain (BC), Technology Notary in Data Driven Marketing (DDM) Contracts [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2021
Today, Data Driven Marketing is challenged by the supply of vague data, inconsistencies between them and fraud through advertising in the digital marketing ecosystem.
Ermal Haxhiaj, Bia Çera
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A clinical and archaeological study of Schmorl’s Nodes: using clinical data to understand the past [PDF]

open access: yes, 2006
This study of Schmorl 's nodes in British populations past and present attempts to reach a better understanding of the origins and aetiology of Schmorl' s nodes and their impact upon the vertebral column in relation to age, sex, pre-existing skeletal ...
McNaught, Janet Mary   +1 more
core  

Nodes

open access: yes, 2022
List of authors, identification specialists, andcollections localities, along with their respective coordinates.
Thiago Silva (5563847)
core   +1 more source

Oribatid mites (Acariformes: Sarcoptiformes) in Sub-Antarctic Islands and Antarctica: a track analysis

open access: yesУкраїнський антарктичний журнал
Southern non-marine mites are widely distributed in the continents that developed out of the macrocontinent Gondwana, with similar groups found in Australia, New Zealand, Sub-Antarctic Islands, and southern South America.
Patricio R. De los Ríos-Escalante   +2 more
doaj   +1 more source

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