Results 111 to 120 of about 906 (143)

The clinical missense variant E282K in PPP3CA/calcineurin shifts substrate dephosphorylation by altering active site recruitment. [PDF]

Nat Commun
Shirakawa KT, Parikh T, Machado LESF, Poimenidou G, Nguyen HT, Dell'Acqua ML, Kettenbach AN, Page R, Peti W.   +8 more
europepmc   +1 more source

Prodrug approach for the cellular delivery of polyanionic inhibitors of protein kinase CK2 [PDF]

, 2014
Saaver, Siiri
core  

Genome Mining of Pseudanabaena galeata CCNP1313 Indicates a New Scope in the Search for Antiproliferative and Antiviral Agents. [PDF]

Microorganisms
Grabski M, Gawor J, Cegłowska M, Gromadka R, Mazur-Marzec H, Węgrzyn G.   +5 more
europepmc   +1 more source

Microcystins Exposure and the Risk of Metabolic Syndrome: A Cross-Sectional Study in Central China. [PDF]

Toxins (Basel)
Feng S, Zeng Y, Song F, Shen M, Yang F.
europepmc   +1 more source

Health and Environmental Impacts of Cyanobacteria and Cyanotoxins from Freshwater to Seawater. [PDF]

Toxins (Basel)
Villalobos T, Suárez-Isla B, Garcia C.
europepmc   +1 more source

Occurrence of cyanobacteria producers of cyanotoxins and their toxins in El Pañe reservoir - Arequipa - Peru [PDF]

Victor Hugo Rodriguez Uro
core  

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Cloud-point extraction of nodularin-R from natural waters

Analytica Chimica Acta, 2004
Abstract A cloud-point extraction (CPE) technique for the determination of a cyanobacterial hepatotoxin, nodularin-R, in aqueous media using a cationic surfactant, tricaprylmethylammonium chloride (Aliquat-336), was developed. Cloud-point phase separation of Aliquat-336 at ambient temperature was induced by the addition of sodium sulfate. The Aliquat-
Paul K S Lam
exaly   +21 more sources

Mass spectrometric detection and quantification of nodularin‐R in flounder livers

Environmental Toxicology, 2003
AbstractLivers of flounders caught during August 1995 from the western Gulf of Finland and the Archipelago Sea were analyzed for nodularin‐R (NODLN) by matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry and liquid chromatography‐electrospray ionization‐mass spectrometry (LC‐MS).
Krister, Karlsson, Vesa, Sipiä, Eberhard, Krause, Jussi, Meriluoto, Stephan, Pflugmacher   +4 more
openaire   +4 more sources

Acyloxymethyl Esterification of Nodularin-R and Microcystin-LA Produces Inactive Protoxins that Become Reactivated and Produce Apoptosis inside Intact Cells [PDF]

Journal of Medicinal Chemistry, 2009
We report the esterification of the carboxyl groups of the cyclic peptide toxins nodularin-R and microcystin-LA to produce stable diacetoxymethyl and dipropionyloxymethyl ester derivatives. The derivatives had no activity but were reactivated upon esterase treatment.
Lars, Herfindal, Franciszek, Kasprzykowski, Frank, Schwede, Leszek, Łankiewicz, Kari E, Fladmark, Joanna, Łukomska, Matti, Wahlsten, Kaarina, Sivonen, Zbigniew, Grzonka, Bernd, Jastorff, Stein Ove, Døskeland   +10 more
openaire   +2 more sources