Results 111 to 120 of about 219,811 (315)

The diagnostic value of CT-guided percutaneous lung biopsy in atypical pulmonary hamartoma and pulmonary sclerosing pneumocytoma

open access: yesFrontiers in Oncology
ObjectiveThis study aims to evaluate the clinical utility of computed tomography-guided percutaneous lung biopsy (CT-PLB) in the diagnosis of atypical pulmonary hamartoma (APH) and pulmonary sclerosing pneumocytoma (PSP).MethodsThis retrospective study ...
Meng Li   +7 more
doaj   +1 more source

An experimental and modelling exploration of the host-sanction hypothesis in legume-rhizobia mutualism [PDF]

open access: yes, 2008
Despite the importance of mutualism as a key ecological process, its persistence in nature is difficult to explain since the existence of exploitative, 'cheating' partners that could erode the interaction is common. By analogy with the proposed
Jose Ruiz-Sainz   +7 more
core  

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang   +14 more
wiley   +1 more source

Benign laryngeal lesions: review of 329 cases in a single center

open access: yesNorthwestern Medical Journal
Aim: Benign laryngeal lesions are non-neoplastic growths of abnormal tissue on the laryngeal mucosa. They are significant because they can affect the laryngeal functions of voice production, respiration, and deglutition.
Hatice Bengü Çobanoğlu   +3 more
doaj   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

open access: yesAdvanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian   +13 more
wiley   +1 more source

Precise Control of Charge–Structure Coupling in Polyamide Membranes for Mono‐ and Divalent Ion Separation

open access: yesAdvanced Science, EarlyView.
A zwitterionic copolymer, Poly(2‐methacryloyloxyethyl phosphorylcholine‐co‐2‐aminoethyl methacrylate hydrochloride) (P(MPC‐co‐AEMA)) copolymers, with tunable MPC/AEMA ratios, is grafted onto the polyamide (PA) selective layer via secondary interfacial polymerization. Balancing reactive anchoring segments (AEMA) and zwitterionic segments (MPC) regulated
Shaofan Duan   +13 more
wiley   +1 more source

Comparison of three commercial AI tools for detection and malignancy assessment of incidental lung nodules

open access: yesFrontiers in Medicine
ObjectivesIncidental pulmonary nodules are common on computed tomography (CT), and management typically relies on size and volume. Artificial intelligence (AI)-based tools show promise in nodule detection and risk assessment, but their clinical utility ...
Oguzhan Tokur   +28 more
doaj   +1 more source

ROC Curve for CXR: Nodule.

open access: yes, 2020
ROC Curve for CXR: Nodule.
Alyssa Long (6729959)   +4 more
core   +1 more source

Matrix Stiffness Orchestrates Mesenchymal Stem Cell Lineage Commitment Toward Osteogenesis and Adipogenesis Through the PIEZO1/SP1/STC2 Axis

open access: yesAdvanced Science, EarlyView.
Matrix stiffness directs mesenchymal stem cell lineage commitment through PIEZO1‐dependent activation of the SP1/STC2 pathway. Stiff matrices favor osteogenesis and suppress adipogenesis, whereas the loss of PIEZO1 function impairs early bone formation. STC2 retains lineage‐regulatory activity even when PIEZO1 is inactive.
Shuo Zhang   +12 more
wiley   +1 more source

Chemical composition of a manganese nodule from the sea of Japan off Izu Islands

open access: yes, 1955
Chemical composition of a manganese nodule from the sea of Japan off Izu ...
Niino, Hiroshi, Hiroshi Niino (6971444)
core   +1 more source

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