Results 31 to 40 of about 1,885,709 (264)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FIQ: A Fastener Inspection and Quantization Method Based on Mask FRCN
Applied SciencesRail-fastening components are essential for ensuring the safety of urban rail systems by securing rails to sleepers. Traditional inspection methods rely heavily on manual labor and are inefficient.
Zhanhao Shang +4 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Journal of Function Spaces, 2022 Aiming at vehicles will produce shocks and vibrations for various reasons in the process of transportation and handling, any shock and vibration that exceeds the regulations would cause damage to the nuclear fuel being transported.
Han Yong +6 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Indian Journal of Public Health, 2014 Background: It is hypothesized that exposure to transportation noise is associated with an increased risk of cardiovascular disease among adult population. The present study further explores this association in the light of new findings. The objective of
Dibyendu Banerjee
doaj +1 more source
Experimental research on vibration and noise of rail conveyor
Energy Reports, 2021 Rail Conveyor is a highly energy-efficient and cost-effective bulk material transportation system, which merges the benefits of both belt conveyor technology and railway. Reducing vibration and noise is a key problem in the design of rail conveyor system,
Nini Hao +3 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Geoplanning: Journal of Geomatics and Planning, 2023 The intricate relationship between aviation-related noise pollution, demographic factors, and tree canopy cover can hold significant implications for targeted interventions promoting environmental equity, sonic justice, and sustainable urban development.
Mayra Ivelisse Rodriguez Gonzalez +1 more
doaj +1 more source