Results 51 to 60 of about 1,885,709 (264)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Long-term exposure to transportation noise in relation to global cognitive decline and cognitive impairment: Results from a Swedish longitudinal cohort

open access: yesEnvironment International
Background and aims: Transportation noise is an environmental exposure with mounting evidence of adverse health effects. Besides the increased risk of cardiovascular and metabolic diseases, recent studies suggest that long-term noise exposure might ...
Jing Wu   +7 more
doaj   +1 more source

Noise Assessment of the Southeastern Pennsylvania Transportation Authority Heavy Rail Transit System

open access: yes
The report describes the noise climate on and near the Southeastern Pennsylvania Transportation Authority, (SEPTA), Broad Street Subway and Market-Frankford Elevated Line.
Spencer, R. H.   +2 more
core   +1 more source

State Transportation Statistics 2015 [PDF]

open access: yes
The Bureau of Transportation Statistics (BTS) presents State Transportation Statistics 2015, a statistical profile of transportation in the 50 States and the District of Columbia.
Nguyen, Long X.   +2 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Investigating the Effect of Urban Traffic Noise Pollution on University Students\' Cognitive Performance: A Simulated Study

open access: yesJournal of Mazandaran University of Medical Sciences, 2022
Background and purpose: Cognitive performance in workplace encompasses a wide range of work-related psychological activities. Meanwhile, personality traits as a mediating variable has a determining role in mental functions and occurrence of errors.
Siavash EtemadiNezhad   +4 more
doaj  

Process Implementation for the System Evaluation of new Low-Noise STOL Transportation Concepts [PDF]

open access: yes, 2009
The German Aerospace Center (DLR) has initiated the project Quiet Short Take-Off and Landing (QSTOL) to set up a multidisciplinary analysis process for new low-noise STOL transportation concepts.
Schneider, Oliver   +4 more
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Residential green is associated with reduced annoyance to road traffic and railway noise but increased annoyance to aircraft noise exposure

open access: yesEnvironment International, 2020
Background: In recent years, residential green and availability of neighbourhood green spaces came into focus as a potential means to reduce transportation noise annoyance.
Beat Schäffer   +4 more
doaj   +1 more source

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