Results 51 to 60 of about 1,380 (217)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
FIQ: A Fastener Inspection and Quantization Method Based on Mask FRCN
Applied SciencesRail-fastening components are essential for ensuring the safety of urban rail systems by securing rails to sleepers. Traditional inspection methods rely heavily on manual labor and are inefficient.
Zhanhao Shang +4 more
doaj +1 more source
Indian Journal of Public Health, 2014 Background: It is hypothesized that exposure to transportation noise is associated with an increased risk of cardiovascular disease among adult population. The present study further explores this association in the light of new findings. The objective of
Dibyendu Banerjee
doaj +1 more source
Geoplanning: Journal of Geomatics and Planning, 2023 The intricate relationship between aviation-related noise pollution, demographic factors, and tree canopy cover can hold significant implications for targeted interventions promoting environmental equity, sonic justice, and sustainable urban development.
Mayra Ivelisse Rodriguez Gonzalez +1 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Noise-induced transport at zero temperature [PDF]
Journal of Physics A: Mathematical and General, 1998 We consider a particle in the over-damped regime at zero temperature under the influence of a sawtooth potential and of a noisy force, which is correlated in time. A current occurs, even if the mean of the noisy force vanishes. We calculate the stationary probability distribution and the stationary current.
Kohler, Heiner, Mielke, Andreas
openaire +3 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Roadway Traffic Sound Measured up on a High-Rise Building–The Sound-Level’s Statistical Normality
IEEE Access, 2022 Percentile-value ceilings/thresholds have been mandated by governments around the world on roadway traffic sound-level. Such percentile values, by definition, change with the sound-level’s underlying probability distribution, i.e., the same ...
Muhammad Muaz +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source