Results 81 to 90 of about 385,001 (285)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Reconstructing the Traffic State by Fusion of Heterogeneous Data

open access: yes, 2009
We present an advanced interpolation method for estimating smooth spatiotemporal profiles for local highway traffic variables such as flow, speed and density.
Bertini   +21 more
core   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu   +5 more
wiley   +1 more source

Long-term exposure to transportation noise and its association with adiposity markers and development of obesity

open access: yesEnvironment International, 2018
The contribution of different transportation noise sources to metabolic disorders such as obesity remains understudied. We evaluated the associations of long-term exposure to road, railway and aircraft noise with measures of obesity and its subphenotypes
Maria Foraster   +13 more
doaj   +1 more source

A Comparison of the Social Costs of Air and Highway [PDF]

open access: yes
This paper provides a comprehensive survey of the literature on the measures of social costs, providing an indication of the state of engineering and economic literature.
Adib Kanafani   +2 more
core  

Computer supported estimation of input data for transportation models [PDF]

open access: yes, 2010
Control and management of transportation systems frequently rely on optimization or simulation methods based on a suitable model. Such a model uses optimization or simulation procedures and correct input data.
Cenek, Petr   +2 more
core   +1 more source

Multi-Output Gaussian Processes for Crowdsourced Traffic Data Imputation

open access: yes, 2019
Traffic speed data imputation is a fundamental challenge for data-driven transport analysis. In recent years, with the ubiquity of GPS-enabled devices and the widespread use of crowdsourcing alternatives for the collection of traffic data, transportation
Henrickson, Kristian   +2 more
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Time-Frequency Analysis of Horizontal Vibration for Vehicle-Track System Based on Hilbert-Huang Transform

open access: yesAdvances in Mechanical Engineering, 2013
Relationship between track alignment irregularity and car body horizontal vibration acceleration is analyzed by using Hilbert-Huang Transform (HHT). Actual measured alignment irregularity and car body horizontal vibration acceleration are decomposed by ...
Zaiwei Li, Songliang Lian, Yuelei He
doaj   +1 more source

Realizing modeling and mapping tools to study the upsurge of noise pollution as a result of open-cast mining and transportation activities

open access: yesNoise and Health, 2018
Introduction: In open-cast mines, noise pollution has become a serious concern due to the extreme use of heavy earth moving machinery (HEMM). Materials and Methods: This study is focused to measure and assess the effects of the existing noise levels of ...
Satish K Lokhande   +4 more
doaj   +1 more source

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