In real systems, the unpredictable jump changes of the random environment can induce the critical transitions (CTs) between two non-adjacent states, which are more catastrophic. Taking an asymmetric Lévy-noise-induced tri-stable model with desirable, sub-
Jin-Zhong Ma +5 more
semanticscholar +1 more source
Neuroinflammation mediates noise-induced synaptic imbalance and tinnitus in rodent models
Hearing loss is a major risk factor for tinnitus, hyperacusis, and central auditory processing disorder. Although recent studies indicate that hearing loss causes neuroinflammation in the auditory pathway, the mechanisms underlying hearing loss–related ...
Wei-Hua Wang +12 more
semanticscholar +1 more source
Vesicular Glutamatergic Transmission in Noise-Induced Loss and Repair of Cochlear Ribbon Synapses
Noise-induced excitotoxicity is thought to depend on glutamate. However, the excitotoxic mechanisms are unknown, and the necessity of glutamate for synapse loss or regeneration is unclear. Despite absence of glutamatergic transmission from cochlear inner
Kyunghee X. Kim +12 more
semanticscholar +1 more source
Are the comfort classes noise and vibration levels on board really suitable?
In shipbuilding industry, comfort is a relevant issue both for crew members and passengers. A comfortable environment enables crew members to perform accurately their tasks and it is an effective factor contributing to the satisfaction of passengers ...
Flavia D'Agostin +2 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Evaluation of Occupational Exposure to Noise and Its Effect on Hearing Loss of Workers in a Cement Factory in Northern Iran [PDF]
Background and: Industrial noise affects the health of workers and can disrupt the daily communication of workers. The aim of this study is to evaluate occupational exposure and investigate the hearing loss of workers in the two sections of cement mill ...
Hamidreza Mehri +3 more
doaj
Noise-induced loss of sensory hair cells is mediated by ROS/AMPKα pathway
The formation of reactive oxygen species (ROS) is a well-documented process in noise-induced hearing loss (NIHL). We have also previously shown that activation of 5’ adenosine monophosphate (AMP)-activated protein kinase (AMPKα) at its catalytic residue ...
Fan Wu, Hao Xiong, Su-Hua Sha
semanticscholar +1 more source
The Measurement and Analysis of the Disc/Pad Interface Dynamic Centre of Pressure and its Influence on Brake Noise. [PDF]
This paper discusses the measurement of the dynamic centre of pressure (CoP) of a brake pad during a normal braking event using a modified 12-piston opposed calliper. The modifications allow the centre of pressure to be controlled both radially and along
John D. Fieldhouse +5 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Pejvakin-mediated pexophagy protects auditory hair cells against noise-induced damage
Significance Noise-induced hearing loss is a highly prevalent form of sensorineural hearing impairment affecting individuals of all ages. Noise exposure triggers a rapid increase in reactive oxygen species (ROS) levels, causing oxidative damage to ...
J. Defourny +5 more
semanticscholar +1 more source

