Results 81 to 90 of about 2,763,116 (335)

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Acoustic characteristics of a cylindrical shell coupled to an acoustic cavity under complex excitations

AIP Advances, 2022
In this research, we analyze the acoustic–vibration coupling of liquid-filled cylindrical shells under complex excitations. A calculation model to determine the acoustic characteristics and steady-state response of a cylindrical shell coupled to an ...
Suwei Yuan, Haichao Zhu, Jiuxiao Hou, Jinlong Liao   +3 more
doaj   +1 more source

Exam‐level analysis of lecture capture viewing and student exam performance

FEBS Open Bio, EarlyView.
This study asks how lecture capture relates to exam performance in biology courses with three noncumulative exams. Mixed‐effects modeling separated between‐students from within‐student effects on exam %. Students who watched more recordings earned higher grades, but viewing spikes above a student's own mean, consistent with cramming, predicted small ...
Kirk Hillsley
wiley   +1 more source

Intelligent Alignment Control for Floating Raft Air Spring Mounting System Under Coupled Hull–Raft Deformation

Journal of Marine Science and Engineering
Shaft alignment is adversely affected by the increasingly severe coupled hull–raft deformation in deep-diving, highly integrated submersibles, thereby compromising operational safety and potentially amplifying vibration noise.
Jian-Wei Cheng, Wen-Jun Bu, Ze-Chao Hu, Jun-Qiang Fu, Hong-Rui Zhang, Liang Shi   +5 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Study on the influence of working condition variation on lubrication characteristics of EHA internal pump

Scientific Reports
The operational characteristics of Electro-Hydraulic Actuator(EHA) result in the EHA internal pump facing complex conditions of variable speed, pressure and even direction, resulting in poor lubrication state of friction pairs.
Yantao Zhang, Zongbin Chen, Jun Che, Jian Liao   +3 more
doaj   +1 more source

Longitudinal Study of Salivary Biomarkers in the Definition of Clinico‐Molecular Progression of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
Longitudinal changes in salivary biomarkers in Parkinson’s disease (PD) from early (T0) to 4‐year follow‐up (T1), quantified by ELISA: oligomeric and total α‐synuclein, total and phosphorylated tau, MAP1LC3B (autophagy), and TNFa (inflammation). Blue arrows indicate direction of change at T1 vs T0 (up = increase; down = decrease).
Maria Ilenia De Bartolo, Daniele Belvisi, Matteo Costanzo, Claudia Caturano, Francesco Emanuele Bellomi, Carolina Cutrona, Flavia Aiello, Giorgio Leodori, Massimo Marano, Romina Mancinelli, Antonella Conte, Giovanni Fabbrini, Alfredo Berardelli, Giorgio Vivacqua   +13 more
wiley   +1 more source

ESL-YOLO: Edge-Aware Side-Scan Sonar Object Detection with Adaptive Quality Assessment

Journal of Marine Science and Engineering
Focusing on the problem of insufficient detection accuracy caused by blurred target boundaries, variable scales, and severe noise interference in side-scan sonar images, this paper proposes a high-precision detection network named ESL-YOLO, which ...
Zhanshuo Zhang, Changgeng Shuai, Chengren Yuan, Buyun Li, Jianguo Ma, Xiaodong Shang   +5 more
doaj   +1 more source

Assessing a Mitochondrial Disease Treatment via a Novel Statistical Technique for Accelerometer Data

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Therapeutic development for mitochondrial diseases, rare genetic disorders with pathogenic defects of oxidative phosphorylation, is hindered by unsatisfactory outcome measures. To address this problem, we provide the first clinical application of a novel, bias‐adjusted outcome measure of acceleration across a range of subjects ...
Ian W. McKeague, Kristin Engelstad, Yue Ge, Amber Tucker, Shufang Li, Jasim Uddin, Ziwei Zhao, John L. P. Thompson, Michio Hirano   +8 more
wiley   +1 more source

Stiffness analysis and structural optimization design of an air spring for ships

Scientific Reports
An air spring (AS) for ships must have the structural strength of its bellows enhanced considerably to ensure its reliability under high internal pressure and strong impact.
Yuqiang Cheng, Hua Gao, Jianguo Ma, Changgeng Shuai   +3 more
doaj   +1 more source