Results 21 to 30 of about 593,514 (265)

Numerical modeling techniques for noise emission of free railway wheels

open access: yesRailway Engineering Science
In this article, we consider the numerical prediction of the noise emission from a wheelset in laboratory conditions. We focus on the fluid–structure interaction leading to sound emission in the fluid domain by analyzing three different methods to ...
Linus Taenzer   +4 more
doaj   +1 more source

A Method for Determining the Optimal Location of a Distributed Sensor/Actuator

open access: yesShock and Vibration, 1994
The optimal location problem of distributed sensor/actuator for observation and control of a flexible structure is investigated. Using a property of controllability and observability grammian matrices, this approach employs a nonlinear optimization ...
Byeongsik Ko   +2 more
doaj   +1 more source

Comparative study of surface integral methods in aeroacoustic prediction

open access: yesFrontiers in Physics, 2023
Introduction: Surface integral methods based on the acoustic analogy and Kirchhoff formulation are widely employed in computational aeroacoustics. The computational accuracy is usually highly dependent on the selections of the acoustic prediction method ...
Chen Xu   +5 more
doaj   +1 more source

Adjusting Phenotypes by Noise Control

open access: yesPLoS Computational Biology, 2012
Genetically identical cells can show phenotypic variability. This is often caused by stochastic events that originate from randomness in biochemical processes involving in gene expression and other extrinsic cellular processes. From an engineering perspective, there have been efforts focused on theory and experiments to control noise levels by ...
Kyung Hyuk Kim, Herbert M. Sauro
openaire   +4 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Effects of Background Sounds on Annoyance Reaction to Foreground Sounds in Psychoacoustic Experiments in the Laboratory: Limits and Consequences

open access: yesApplied Sciences, 2019
In a variety of applications, e.g., psychoacoustic experiments, virtual sound propagation demonstration, or synthesized noise production, noise samples are played back in laboratories.
Armin Taghipour, Eduardo Pelizzari
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Study on the impact of Gurney flap parameters on rotor performance improvement

open access: yesHangkong gongcheng jinzhan
At present, most of the research on installing Gurney flaps is focused on two-dimensional airfoils. The three-dimensional blade model is established to investigate the influence of different Gurney flap parameters on rotor aerodynamic performance ...
LIU Shaoteng   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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