Results 31 to 40 of about 593,514 (265)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
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AIP AdvancesIn this study, we designed a single-opening Helmholtz chamber type acoustic metamaterial with two sides. The complexity of the open channel results in the material having a low frequency of the first sound insulation peak and excellent sound insulation ...
PeiZhou Hu +5 more
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Nonlinear Engineering, 2017 This research investigates the nonlinear behavior and stability of an elastic suspended cable system under combined parametric and external excitations, with an approach of higher accuracy and reliability.
Dai Liming, Xia Dandan, Chen Changping
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Data in Brief, 2023 Rotating machines are often operated under various operating conditions. However, the characteristics of the data varies with their operating conditions.
Wonho Jung +4 more
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Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
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Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Effect of offset distances for rod-airfoil interaction noise
Frontiers in Physics, 2023 The noise generated by the interaction between the wake of rods and airfoils is a universal phenomenon in the engineering field. The noise generation mechanism is mainly caused by the violent changes of the pulsating pressure on the airfoil surface ...
Shujie Jiang +6 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Road traffic noise and registry based use of sleep medication
Environmental Health, 2017 Background Road traffic noise has been associated with adverse health effects including sleep disturbances. Use of sleep medication as an indicator of sleeping problems has rarely been explored in studies of the effects of traffic noise.
Jorunn Evandt +8 more
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