Results 31 to 40 of about 569,184 (264)

Nonlinear Responses and Stability of an Elastic Suspended Cable System Subjected to Parametrical External Excitations

Nonlinear Engineering, 2017
This research investigates the nonlinear behavior and stability of an elastic suspended cable system under combined parametric and external excitations, with an approach of higher accuracy and reliability.
Dai Liming, Xia Dandan, Chen Changping
doaj   +1 more source

Vibration, acoustic, temperature, and motor current dataset of rotating machine under varying operating conditions for fault diagnosis

Data in Brief, 2023
Rotating machines are often operated under various operating conditions. However, the characteristics of the data varies with their operating conditions.
Wonho Jung, Seong-Hu Kim, Sung-Hyun Yun, Jaewoong Bae, Yong-Hwa Park   +4 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Low-frequency acoustic isolation performance of Helmholtz cavity acoustic metamaterials with bilateral single openings

AIP Advances
In this study, we designed a single-opening Helmholtz chamber type acoustic metamaterial with two sides. The complexity of the open channel results in the material having a low frequency of the first sound insulation peak and excellent sound insulation ...
PeiZhou Hu, Jing-Bo Zhao, Hong Liu, XiaoSheng Zhang, Hong Yao, Guang-jun Zhang   +5 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Effect of offset distances for rod-airfoil interaction noise

Frontiers in Physics, 2023
The noise generated by the interaction between the wake of rods and airfoils is a universal phenomenon in the engineering field. The noise generation mechanism is mainly caused by the violent changes of the pulsating pressure on the airfoil surface ...
Shujie Jiang, Lanqing Li, Xiaokun Guo, Xiaokun Guo, Weiming Zhao, Rongping Zhang, Chao Wang   +6 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A Numerical Study of the Wind Speed Effect on the Flow and Acoustic Characteristics of the Minor Cavity Structures in a Two-Wheel Landing Gear

Applied Sciences, 2021
The landing gear is widely concerned as the main noise source of airframe noise. The flow characteristics and aerodynamic noise characteristics of the landing gear were numerically simulated based on Large Eddy Simulation and Linearized Euler Equation ...
Longlong Huang, Kun Zhao, Junbiao Liang, Victor Kopiev, Ivan Belyaev, Tian Zhang   +5 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source