Results 51 to 60 of about 649,990 (312)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Low-frequency acoustic isolation performance of Helmholtz cavity acoustic metamaterials with bilateral single openings

open access: yesAIP Advances
In this study, we designed a single-opening Helmholtz chamber type acoustic metamaterial with two sides. The complexity of the open channel results in the material having a low frequency of the first sound insulation peak and excellent sound insulation ...
PeiZhou Hu   +5 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Nonlinear Active Noise Control

open access: yes, 2004
Publication in the conference proceedings of EUSIPCO, Viena, Austria ...
SICURANZA, GIOVANNI, A. CARINI
openaire   +4 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Effect of offset distances for rod-airfoil interaction noise

open access: yesFrontiers in Physics, 2023
The noise generated by the interaction between the wake of rods and airfoils is a universal phenomenon in the engineering field. The noise generation mechanism is mainly caused by the violent changes of the pulsating pressure on the airfoil surface ...
Shujie Jiang   +6 more
doaj   +1 more source

Health aspects associated with wind turbine noise : Results from three field studies [PDF]

open access: yes, 2011
Wind farms are a new source of environmental noise. The impact of wind turbine noise on health and well-being has not yet been well-established and remains under debate.
Pedersen, Eja   +2 more
core   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Road traffic noise and registry based use of sleep medication

open access: yesEnvironmental Health, 2017
Background Road traffic noise has been associated with adverse health effects including sleep disturbances. Use of sleep medication as an indicator of sleeping problems has rarely been explored in studies of the effects of traffic noise.
Jorunn Evandt   +8 more
doaj   +1 more source

A Numerical Study of the Wind Speed Effect on the Flow and Acoustic Characteristics of the Minor Cavity Structures in a Two-Wheel Landing Gear

open access: yesApplied Sciences, 2021
The landing gear is widely concerned as the main noise source of airframe noise. The flow characteristics and aerodynamic noise characteristics of the landing gear were numerically simulated based on Large Eddy Simulation and Linearized Euler Equation ...
Longlong Huang   +5 more
doaj   +1 more source

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