Results 61 to 70 of about 649,990 (312)

Noise shielding models for the conceptual design of unconventional aircraft [PDF]

open access: yes, 2018
Air traffic growth and the expansion of urban areas around airports make the aviation community noise a key aspect of aircraft design. The analysis of innovative configurations is becoming activity of primary interest within the scientific community. The
Centracchio F.   +3 more
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Case history : factory noise prediction using ray tracing : experimental validation and the effectiveness of noise control measures [PDF]

open access: yes, 1989
Factory-noise prediction models are invaluable in allowing worker noise-exposure levels in a factory to be evaluated prior to construction and, if necessary, for modifications to be made or noise-control measures to be evaluated.
Hodgson, Murray, Hodgson, M. R.
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Tunable photo-responsive elastic metamaterials

open access: yesNature Communications, 2020
Here, the authors present a light-responsive elastic metamaterial whose transmission spectrum can be tuned by light stimuli. More specifically, we demonstrate that an appropriate laser illumination is effective in reversibly widening an existing ...
Antonio S. Gliozzi   +5 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s)

open access: yesParticle and Fibre Toxicology, 2018
Background Exposure to traffic-derived particulate matter (PM), such as diesel exhaust particles (DEP), is a leading environmental cause of cardiovascular disease (CVD), and may contribute to endothelial dysfunction and development of atherosclerosis. It
Bendik C. Brinchmann   +15 more
doaj   +1 more source

The acoustic of a courtyard [PDF]

open access: yes, 2018
This paper shows the results of acoustic measurements carried out inside a courtyard of the “Reggia of Caserta” (Italy) without audience, and with the aid of a software for architectural acoustics the acoustic characteristics, with audience, were ...
Iannace, Gino   +2 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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