Results 71 to 80 of about 11,122,120 (305)

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Effects of noise type on listening effort: relationship between subjective ratings and objective measurements

, 2017
The present study investigates the relationship between the self-rated effort when listening to speech in adverse conditions, and response time, taken as a measure of the cognitive resources deployed for interpreting and responding to the auditory ...
Chiara Visentin, Nicola Prodi
core  

Noise and cardiovascular disease: A review of the literature 2008-2011

Noise and Health, 2012
The association between noise and cardiovascular disease has been studied for several decades and the weight of evidence clearly supports a causal link. Nevertheless, many questions remain, such as the magnitude and threshold level for adverse effects of
Hugh Davies, Irene Van Kamp
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Noise Effects on Detection and Localization of Faults for Unified Power Flow Controller-Compensated Transmission Lines Using Traveling Waves

Electricity
This paper presents a comprehensive analysis of the effects of noise on the detection and localization of faults in transmission lines compensated with a unified power flow controller using traveling wave-based methods.
Javier Rodríguez-Herrejón, Enrique Reyes-Archundia, Jose A. Gutiérrez-Gnecchi, Marcos Gutiérrez-López, Juan C. Olivares-Rojas   +4 more
doaj   +1 more source

The associations between noise sensitivity, reported physical and mental health, perceived environmental quality, and noise annoyance

Noise and Health, 2010
One hundred and ninety residents around Frankfurt Airport (46% female; 17-80 years) were interviewed concerning noise annoyance due to transportation noise (aircraft, road traffic), perceived mental and physical health, perceived environmental quality ...
Dirk Schreckenberg, Barbara Griefahn, Markus Meis   +2 more
doaj   +1 more source

Aircraft Noise Indexes for Effect Oriented Noise Assessment

Acta Acustica united with Acustica, 2010
This article discusses aircraft noise effect assessment with noise effect indexes, such as have recently been developed for noise monitoring purposes at the airports of Zurich and Frankfurt. Aircraft noise indexes are noise assessment instruments that express the overall effects of aircraft noise as a single figure which reflects the total amount of ...
Brink, M, Schreckenberg, D, Thomann, G, Basner, M   +3 more
openaire   +2 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source