Noise exposure in occupational setting associated with elevated blood pressure in China
Background Hypertension is the primary out-auditory adverse outcome caused due to occupational noise exposure. This study investigated the associations of noise exposure in an occupational setting with blood pressure and risk of hypertension.
Shuchang Chen+8 more
doaj +1 more source
Study on the impact of noise exposure on cognitive function
Noise, as one of the most common harmful environmental factors in our daily lives, can lead to hearing loss with prolonged exposure. More seriously, it can negatively affect cognitive function. The impact of noise exposure on cognitive abilities involves
QIU Chunqin+3 more
doaj +1 more source
Hearing in young adults. Part II: The effects of recreational noise exposure
Great concern arises from recreational noise exposure, which might lead to noise-induced hearing loss in young adults. The objective of the current study was to evaluate the effects of recreational noise exposure on hearing function in young adults.
Hannah Keppler+2 more
doaj +1 more source
Spatial evaluation of environmental noise with the use of participatory sensing system in Singapore
Existing studies in Singapore on environmental noise are scarce and limited in scale due to the need for expensive equipment and sophisticated modelling expertise.
Diong Huey Ting+2 more
doaj +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
Measuring method of occupational non-Gaussian noise exposure based on kurtosis adjustment
The existing measuring methods of noise exposure on the basis of equal energy hypothesis are applicable to Gaussian noise while not fully applicable to non-Gaussian noise.
Yong HU+5 more
doaj +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Repeated Moderate Noise Exposure in the Rat—an Early Adulthood Noise Exposure Model [PDF]
In this study, we investigated the effects of varying intensity levels of repeated moderate noise exposures on hearing. The aim was to define an appropriate intensity level that could be repeated several times without giving rise to a permanent hearing loss, and thus establish a model for early adulthood moderate noise exposure in rats.
Paula Mannström+2 more
openaire +3 more sources
Stage‐Dependent Inhibitory Connectivity in Striatal‐Motor Circuit in Huntington's Disease
ABSTRACT Background Elucidating dysfunctional connectivity patterns among key brain regions in Huntington's disease (HD) underlying progression may have implications for developing treatment and therapeutic evaluation. Objective Explore the relationship between abnormal spontaneous resting‐state activity and atrophy in HD‐specific brain regions and ...
Yinghua Jing+4 more
wiley +1 more source
Objective This study analyzed longitudinal trajectories of soluble Flt1 (sFlt1) levels, placenta growth factor (PlGF) levels, and sFlt1:PlGF ratios in a cohort of pregnant patients with systemic lupus erythematosus (SLE). Methods Blood samples were collected (14–18, 24–26, 30–32, 34–36, and 38–40 weeks), stored at −80°C, and evaluated for serum levels ...
Nilson R. de Jesús+7 more
wiley +1 more source