Results 61 to 70 of about 669,562 (292)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Optimizing Low Noise Amplifiers: A Two-Stage Approach for Improved Noise Figure and Stability

open access: yesIEEE Access
This study introduces a new design for a low noise amplifier (LNA) consisting of two stages taking advantage of the inherent lossy properties of the input matching components. By doing this, the design balances the minimum noise figure (NF) and stability,
Mohammad Zaid   +6 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Noise and noise figure in microwave receivers [PDF]

open access: yes, 1949
The investigation of noise and noise figure in microwave receivers was commenced in the fall of 1948 at the U. S. Naval Postgraduate School and was continued through the winter in the electronics laboratory of the Glenn L. Martin Company at Middle River,
Murphy, Thomas Watson
core  

Q-Band LNA-Antenna Co-Design: Exploiting Antenna Matching for System Noise Figure Optimization

open access: yesIEEE Journal of Microwaves
This paper presents a novel approach to low noise amplifier (LNA)-antenna co-design in the Q-band frequency range, leveraging the antenna as an integral part of the LNA matching network to achieve broadband noise figure improvement.Unlike conventional ...
Kirill Alekseev   +6 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Design and analysis of high performance low noise oscillators and phase lock loops [PDF]

open access: yes, 2010
The design and implementation of high purity, high speed and power efficient clock generation Integrated Circuits continue to be one the greatest challenges facing IC designers today. In order to address this challenge, this thesis considers the modeling
Ke, Li
core  

Design and Simulation of a Low-Noise Amplifier (LNA) with low power consumption and high gain in 2.4GHz frequency for wireless systems [PDF]

open access: yesJournal of Intelligent Procedures in Electrical Technology, 2016
This paper presents the design and simulation of low-noise amplifier (LNA) with .18CMOS technology in 2.4GHz frequency addressed, the process HSPICE RF simulation software has been done.
Esmaeel Karimi, Ebrahim Borzabadi
doaj  

Realisasi LNA Dua Tingkat dengan Teknik Penyesuai Impedansi Trafo λ/4 dan Lumped Element untuk DVB-T2

open access: yesJurnal Elkomika, 2020
ABSTRAK Digital Video Broadcasting-Second Generation Terrestrial (DVB-T2) merupakan standar internasional yang menaungi pemberlakuan televisi digital saat ini. Pada konfigurasi DVB-T2 terdapat perangkat penerima sinyal di sisi pelanggan.
ASEP KARYANA   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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