Results 31 to 40 of about 3,426,972 (306)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 1915 Map encompasses Newark, Harrison, Kearney, Irvington and East Newark. Ward numbers and boundries are shown in red.
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
SoundCompass: A Distributed MEMS Microphone Array-Based Sensor for Sound Source Localization
Sensors, 2014 Sound source localization is a well-researched subject with applications ranging from localizing sniper fire in urban battlefields to cataloging wildlife in rural areas.
Jelmer Tiete +5 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Mapping Noise from Motorised Transport in the Context of Infrastructure Management
Applied SciencesNoise pollution presents significant challenges for urban infrastructure management, highlighting the need for practical assessment tools such as noise maps.
Piotr Jaskowski +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
IEEE Access, 2023 Fully-supervised object detection and instance segmentation models have accomplished notable results on large-scale computer vision benchmark datasets. However, fully-supervised machine learning algorithms’ performances are immensely dependent on ...
Cathaoir Agnew +5 more
doaj +1 more source
Noise maps for acoustically sensitive navigation [PDF]
SPIE Proceedings, 2004 More and more robotic applications are equipping robots with microphones to improve the sensory information available to them. However, in most applications the auditory task is very low-level, only processing data and providing auditory event information to higher-level navigation routines.
Martinson, Eric, Arkin, Ronald C.
openaire +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source