Results 51 to 60 of about 4,050,179 (333)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

SoundCompass: A Distributed MEMS Microphone Array-Based Sensor for Sound Source Localization

open access: yesSensors, 2014
Sound source localization is a well-researched subject with applications ranging from localizing sniper fire in urban battlefields to cataloging wildlife in rural areas.
Jelmer Tiete   +5 more
doaj   +1 more source

Homogenization for deterministic maps and multiplicative noise [PDF]

open access: yesProceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2013
A recent paper of Melbourne & Stuart (2011 A note on diffusion limits of chaotic skew product flows. Nonlinearity 24 , 1361–1367 (doi:10.1088/0951-7715/24/4/018)) gives a rigorous proof of convergence of a fast–slow deterministic system to a stochastic differential equation with additive noise.
Gottwald, Georg A., Melbourne, Ian
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Mapping Noise from Motorised Transport in the Context of Infrastructure Management

open access: yesApplied Sciences
Noise pollution presents significant challenges for urban infrastructure management, highlighting the need for practical assessment tools such as noise maps.
Piotr Jaskowski   +3 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Quantifying the Effects of Ground Truth Annotation Quality on Object Detection and Instance Segmentation Performance

open access: yesIEEE Access, 2023
Fully-supervised object detection and instance segmentation models have accomplished notable results on large-scale computer vision benchmark datasets. However, fully-supervised machine learning algorithms’ performances are immensely dependent on ...
Cathaoir Agnew   +5 more
doaj   +1 more source

Rendering of Dynamic Road Traffic Noise Map Based on Paramics

open access: yes, 2013
Traffic flow is simplified as equal-interval line source in traditional road traffic noise prediction models. The prediction results of these models are non-dynamic and can only be used to render the static noise maps.
Ma Xia-lin, Cai Ming
semanticscholar   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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