Results 51 to 60 of about 4,050,179 (333)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
SoundCompass: A Distributed MEMS Microphone Array-Based Sensor for Sound Source Localization
Sound source localization is a well-researched subject with applications ranging from localizing sniper fire in urban battlefields to cataloging wildlife in rural areas.
Jelmer Tiete +5 more
doaj +1 more source
Homogenization for deterministic maps and multiplicative noise [PDF]
A recent paper of Melbourne & Stuart (2011 A note on diffusion limits of chaotic skew product flows. Nonlinearity 24 , 1361–1367 (doi:10.1088/0951-7715/24/4/018)) gives a rigorous proof of convergence of a fast–slow deterministic system to a stochastic differential equation with additive noise.
Gottwald, Georg A., Melbourne, Ian
openaire +2 more sources
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Mapping Noise from Motorised Transport in the Context of Infrastructure Management
Noise pollution presents significant challenges for urban infrastructure management, highlighting the need for practical assessment tools such as noise maps.
Piotr Jaskowski +3 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Fully-supervised object detection and instance segmentation models have accomplished notable results on large-scale computer vision benchmark datasets. However, fully-supervised machine learning algorithms’ performances are immensely dependent on ...
Cathaoir Agnew +5 more
doaj +1 more source
Rendering of Dynamic Road Traffic Noise Map Based on Paramics
Traffic flow is simplified as equal-interval line source in traditional road traffic noise prediction models. The prediction results of these models are non-dynamic and can only be used to render the static noise maps.
Ma Xia-lin, Cai Ming
semanticscholar +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source

