Results 51 to 60 of about 1,076,908 (272)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Mapping Noise from Motorised Transport in the Context of Infrastructure Management
Applied SciencesNoise pollution presents significant challenges for urban infrastructure management, highlighting the need for practical assessment tools such as noise maps.
Piotr Jaskowski +3 more
doaj +1 more source
Numerical and experimental study of the effects of noise on the permutation entropy [PDF]
, 2015 We analyze the effects of noise on the permutation entropy of dynamical systems. We take as numerical examples the logistic map and the R\"ossler system.
Masoller, Cristina +3 more
core +3 more sources
Towards Mapping of Noise Impact [PDF]
, 2022 AbstractNoise impact management goes hand in hand with the capability to predict the noise impact on exposed communities. Three tools to that purpose are presented in this chapter: the Noise Management Toolset (NMT), the Demo Virtual Community Tool (VCT) and Dynamic Noise Mapping.
Ferenc Marki +4 more
openaire +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
SoundCompass: A Distributed MEMS Microphone Array-Based Sensor for Sound Source Localization
Sensors, 2014 Sound source localization is a well-researched subject with applications ranging from localizing sniper fire in urban battlefields to cataloging wildlife in rural areas.
Jelmer Tiete +5 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
IEEE Access, 2020 Since lane geometry information can be used for controlling the pose of an intelligent vehicle, a lane geometry map that contains the lane geometry information should have reliable accuracy. For generating the reliable lane geometry map, lane curve which
Seokwon Kim +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source