Results 61 to 70 of about 3,038,203 (289)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Basics of meteorology for outdoor sound propagation and related modelling issues

open access: yesNoise Mapping
Noise from industrial plants, wind farms, ports, and airports ranges long distances and merges with noise from linear transport infrastructures (i.e. roads and railways).
Tombolato Andrea   +4 more
doaj   +1 more source

Variable step strategy for online secondary path modelling in active vibration control systems

open access: yesThe Journal of Engineering, 2018
An online modelling method for secondary path of two distinct variable step-size strategies based on the filtered-x least square (FXLMS) algorithm is proposed.
Xiaojing Yang, Junwen Hu, Shan Li
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Optimal height calculation and modelling of noise barrier

open access: yesMokslas: Lietuvos Ateitis, 2011
Transport is one of the main sources of noise having a particularly strong negative impact on the environment. In the city, one of the best methods to reduce the spread of noise in residential areas is a noise barrier.
Raimondas Grubliauskas, Donatas Butkus
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Impulse Noise Injury Model [PDF]

open access: yesMilitary Medicine, 2016
The new Auditory 4.0 model has been developed for the assessment of auditory outcomes, expressed as temporary threshold shift (TTS) and permanent threshold shift (PTS), from exposures to impulse noise for unprotected ears, including the prediction of TTS recovery.Auditory 4.0 is an empirical model, constructed from test data collected from chinchillas ...
Philemon, Chan, Kevin, Ho, Allen F, Ryan
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Aftershocks in coherent-noise models [PDF]

open access: yesPhysica D: Nonlinear Phenomena, 1998
23 pages, 8 figures, Latex with elsart.cls, revised version accepted for publication in Physica ...
Wilke, C., Altmeyer, S., Martinetz, T.
openaire   +2 more sources

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