Results 61 to 70 of about 3,038,203 (289)
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Basics of meteorology for outdoor sound propagation and related modelling issues
Noise from industrial plants, wind farms, ports, and airports ranges long distances and merges with noise from linear transport infrastructures (i.e. roads and railways).
Tombolato Andrea +4 more
doaj +1 more source
Variable step strategy for online secondary path modelling in active vibration control systems
An online modelling method for secondary path of two distinct variable step-size strategies based on the filtered-x least square (FXLMS) algorithm is proposed.
Xiaojing Yang, Junwen Hu, Shan Li
doaj +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Optimal height calculation and modelling of noise barrier
Transport is one of the main sources of noise having a particularly strong negative impact on the environment. In the city, one of the best methods to reduce the spread of noise in residential areas is a noise barrier.
Raimondas Grubliauskas, Donatas Butkus
doaj +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Impulse Noise Injury Model [PDF]
The new Auditory 4.0 model has been developed for the assessment of auditory outcomes, expressed as temporary threshold shift (TTS) and permanent threshold shift (PTS), from exposures to impulse noise for unprotected ears, including the prediction of TTS recovery.Auditory 4.0 is an empirical model, constructed from test data collected from chinchillas ...
Philemon, Chan, Kevin, Ho, Allen F, Ryan
openaire +2 more sources
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Aftershocks in coherent-noise models [PDF]
23 pages, 8 figures, Latex with elsart.cls, revised version accepted for publication in Physica ...
Wilke, C., Altmeyer, S., Martinetz, T.
openaire +2 more sources

