Results 71 to 80 of about 2,599,514 (283)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
A Four-Stage Method for Active Control with Online Feedback Path Modelling Using Control Signal
Applied Sciences, 2019 The presence of control signal feedback to the reference microphone in feedforward active control systems deteriorates the control performance. A four-stage method is proposed in this paper to carry out online feedback path modelling with the control ...
Somanath Pradhan +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Modelling of road traffic noise
MATEC Web of Conferences, 2018 Effective implementation of the EC Communication relating to urban mobility is dependent on adopting relevant indicators that will allow comprehensive assessment of the measures undertaken under the urban mobility plan.
Bąkowski Andrzej +2 more
doaj +1 more source
Regression modelling of traffic noise pollution
Građevinar, 2013 Noise is distinctive in comparison to pollutants like air, water and soil. It does not leave any residual evidence that would serve as a continuing reminder of its unpleasantness. Models like FHWA, CORTN, STOP and GO are used for traffic noise prediction
Yugananth Pachiappan, Baskar Govindaraj
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Noise MappingEurope is acting to fight noise pollution. The Environmental Noise Directive (2002/49/EC) requires EU Member States to determine the exposure to environmental noise through strategic noise mapping, and elaborate action plans to reduce noise pollution ...
Odeh Omar, Khayyat Aiham, Kocsis Dénes
doaj +1 more source
Industrial noise assessment and modelling in Šiauliai
Mokslas: Lietuvos Ateitis, 2011 One of the most discussed problems of industry is noise pollution. A number of powerful machinery make noise in the industry sector and can cause plenty of diseases for people working in this sector.
Ilona Paožalytė
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source