Results 51 to 60 of about 950,513 (297)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

The Study and Development of BPM Noise Monitoring at the Siam Photon Source

Particles
This study presents the development of a noise-monitoring system for the storage ring at the Siam Photon Source, designed to detect and classify noise patterns in real time using beam position monitor (BPM) data. Noise patterns were categorized into four
Wanisa Promdee, Sukho Kongtawong, Surakawin Suebka, Thapakron Pulampong, Natthawut Suradet, Roengrut Rujanakraikarn, Puttimate Hirunuran, Siriwan Jummunt   +7 more
doaj   +1 more source

Improvement of Noise Stability of Michelson Optical Fiber Voice Monitoring System

IEEE Access, 2021
Optical fiber sensing is a novel sensing technology with the advantages of anti-electromagnetic interference, anti-corrosion and high sensitivity suiting for many special applications.
Yuhan Hu, Qiuheng Song, Hekuo Peng, Qian Xiao   +3 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Detecting a stochastic gravitational wave background with the Laser Interferometer Space Antenna [PDF]

, 2001
The random superposition of many weak sources will produce a stochastic background of gravitational waves that may dominate the response of the LISA (Laser Interferometer Space Antenna) gravitational wave observatory.
Abbasi, R., Abdou, Y., Abu-Zayyad, T., Adams, J., Aguilar, J.A., Ahlers, M., Alba, J.L.B., Andeen, K., Auffenberg, J., Bai, X., Baker, M., Barwick, S.W., Bay, R., Beattie, K., Beatty, J.J., Bechet, S., Becker, J.K., Becker, K.H., Benabderrahmane, M.L., BenZvi, S., Berdermann, J., Berghaus, P., Berley, D., Bernardini, E., Bertrand, D., Besson, D.Z., Bindig, D., Bissok, M., Blaufuss, E., Blumenthal, J., Boersma, D.J., Bohm, C., Bose, D., Boser, S., Botner, O., Braun, J., Brown, A.M., Buitink, S., Carson, M., Chirkin, D., Christy, B., Clem, J., Clercq, C. De, Clevermann, F., Cohen, S., Colnard, C., Cowen, D.F., D'Agostino, M.V., Danninger, M., Daughhetee, J., Davis, J.C., Demirors, L., Denger, T., Depaepe, O., Descamps, F., Desiati, P., DeYoung, T., Diaz-Velez, J.C., Dierckxsens, M., Dreyer, J., Dumm, J.P., Ehrlich, R., Eisch, J., Ellsworth, R.W., Engdegard, O., et al., Euler, S., Evenson, P.A., Fadiran, O., Fazely, A.R., Fedynitch, A., Feusels, T., Filimonov, K., Finley, C., Fischer-Wasels, T., Foerster, M.M., Fox, B.D., Franckowiak, A., Franke, R., Gaisser, T.K., Gallagher, J., Geisler, M., Gerhardt, L., Gladstone, L., Glusenkamp, T., Goldschmidt, A., Goodman, J.A., Grant, D., Griesel, T., Gross, A., Grullon, S., Gurtner, M., Ha, C., Hallgren, A., Halzen, F., Han, K., Hanson, K., Heinen, D., Helbing, K., Herquet, P., Lafebre, S.J., Vries-Uiterweerd, G. de   +101 more
core   +3 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Measurements and Analysis of Sound Reflections from Selected Building Façades

Applied Sciences
This paper presents a study of the effect of the type of exterior cladding material of a building façade on the amount of sound reflection. It was verified whether there is a sound field undisturbed by reflections, similar to the free field, at a ...
Adam Zagubień, Katarzyna Wolniewicz
doaj   +1 more source

Smart Solutions for Recreational Noise Pollution in Turkey

Noise Mapping, 2017
Environmental noise has become an important issue in urban life quality. Policy makers, local authorities and researchers have been trying to solve this issue in a smart way.
Çoban Nilgün Akbulut, Dalkılıç Cengiz, Kaya Sezer, Türkmenoğlu Mevlüt, Çoban Mustafa   +4 more
doaj   +1 more source