Results 31 to 40 of about 347,371 (244)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Non-linear viscoelastic characterization of perfluroelastomer raw rubber
Hecheng xiangjiao gongyeLarge-amplitude oscillatory shear (LAOS) tests were carried out on 1055 B and 2160 B perfluroelastomer raw rubber. The structural differences were explored by analyzing their rheological behavior.
SONG Rong-hao1, LI Zhen-lian2, HUANG Kai-ming2, YANG Rui1, WANG Chen1, SU Zheng-tao1
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Technologies for jet noise reduction in turbofan engines
Aviation, 2012 Turbofan engines are commonly used for commercial transport due to their advantages of higher performance and lower noise. Jet noise is one of the principal noise sources of turbofan aeroplane engines and remains an acute environmental problem that ...
Mofid Gorji-Bandpy, Mohammadreza Azimi
doaj +1 more source
Noise Reduction by Barriers [PDF]
The Journal of the Acoustical Society of America, 1973 A literature review is prepared to summarize the present state of knowledge concerning the field performance of barriers, with particular reference to screen-type barriers on finite impedance ground, to barriers of finite thickness, to right-angle wedges, to multiple barriers, and to effects of wind.
openaire +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Noise reduction algorithm for glueball correlators
Physics Letters B, 2014 We present an error reduction method for obtaining glueball correlators from Monte Carlo simulations of SU(3) lattice gauge theory. We explore the scalar and tensor channels at three different lattice spacings.
Pushan Majumdar +2 more
doaj +1 more source