Results 101 to 110 of about 875,579 (253)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe +7 more
wiley +1 more source
4DRadarRBD: 4D mmWave radar-based road boundary detection in autonomous driving
Frontiers in Signal ProcessingIntroductionDetecting road boundaries, the static physical edges of the available driving area, is important for safe navigation and effective path planning in autonomous driving and advanced driver-assistance systems.
Yuyan Wu, Hae Young Noh
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Constructing Approximations to Bivariate Piecewise-Smooth Functions
AxiomsThis paper demonstrates that the space of piecewise-smooth bivariate functions can be well-approximated by the space of the functions defined by a set of simple (non-linear) operations on smooth uniform tensor product splines.
David Levin
doaj +1 more source
Bayesian DNA copy number analysis
BMC Bioinformatics, 2009 Background Some diseases, like tumors, can be related to chromosomal aberrations, leading to changes of DNA copy number. The copy number of an aberrant genome can be represented as a piecewise constant function, since it can exhibit regions of deletions ...
Hutter Marcus +3 more
doaj +1 more source
Curve and surface reconstruction from noisy samples
, 2009 [[abstract]]©2004-Reconstructing an unknown curve or surface from sample points is an important task in geometric modeling applications. Sample points obtained from real applications are usually noisy. For example, when data sets are obtained by scanning
Poon,Sheung-Hung
core
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
Curve and surface reconstruction from noisy samples
, 2004 Reconstructing an unknown curve or surface from sample points is an important task in geometric modeling applications. Sample points obtained from real applications are usually noisy.
Poon, Sheung-Hung
core
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias +3 more
wiley +1 more source