Results 81 to 90 of about 875,579 (253)
FGSI: distant supervision for relation extraction method based on fine-grained semantic information
Scientific Reports, 2023 Relation extraction is one of the important steps in building a knowledge graph. Its main objective is to extract semantic relationships from identified entity pairs in sentences, playing a crucial role in semantic understanding and knowledge graph ...
Chenghong Sun +5 more
doaj +1 more source
A deconvolution approach to estimation of a common shape in a shifted curves model [PDF]
, 2010 This paper considers the problem of adaptive estimation of a mean pattern in a randomly shifted curve model. We show that this problem can be transformed into a linear inverse problem, where the density of the random shifts plays the role of a ...
Jérémie Bigot +3 more
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
DiagnosticsBackground: Chest X-ray (CXR) imaging is crucial for diagnosing thoracic abnormalities; however, the rising demand burdens radiologists, particularly in resource-limited settings. Method: We used large-scale, diverse public CXR datasets with noisy labels
Farzeen Khalid Khan +6 more
doaj +1 more source
Using the generalized Radon transform for detection of curves in noisy images [PDF]
1996 IEEE International Conference on Acoustics, Speech, and Signal Processing Conference Proceedings, 2002 In this paper the discrete generalized Radon transform will be investigated as a tool for detection of curves in noisy digital images. The discrete generalized Radon transform maps an image into a parameter domain, where curves following a specific parameterized curve form will correspond to a peak in the parameter domain.
openaire +3 more sources
, 2012 Colour photograph of the completed Curve which looms large next to the older buildings of the ...
Hyde, Colin;
core