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Rethinking Parkinson's disease: could dopamine reduction therapy have clinical utility? [PDF]
J NeurolSackner-Bernstein J.
europepmc +1 more source
Role of alpha-synuclein in the regulation of dopamine neurotransmission in the striatum [PDF]
Chadchankar, Heramb
core
Nomifensine-induced dyskinesia.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1985 openaire +1 more source
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Dopaminergic properties of nomifensine
Pharmacology Biochemistry and Behavior, 1982Nomifensine and a proposed dihydroxy metabolite produced stimulation of motor behavior in mice with nomifensine being more potent. Weak cage-climbing behavior (stereotypy) was also produced. The stimulatory effects were greater in mice in which dopamine receptor sensitivity was increased by long-term haloperidol.
G, Gianutsos +3 more
exaly +3 more sources
International Pharmacopsychiatry, 1982
Nomifensine, a representative of a new class of chemical substances, is a compound of low toxicity and of wide therapeutical range. Nomifensine is absorbed very well, has a rapid onset of action, has no sedative effect and does not prolong alcohol-induced anaesthesia. In studies on thymoleptic activity, nomifensine showed a good and persistent activity,
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Nomifensine, a representative of a new class of chemical substances, is a compound of low toxicity and of wide therapeutical range. Nomifensine is absorbed very well, has a rapid onset of action, has no sedative effect and does not prolong alcohol-induced anaesthesia. In studies on thymoleptic activity, nomifensine showed a good and persistent activity,
openaire +2 more sources
Nomifensine and Convulsive Seizures
Human Toxicology, 1987Four cases of convulsive seizures occurring during treatment with nomifensine have been notified to the Committee on the Safety of Medicines of the United Kingdom, and 22 cases have been reported from other countries. The occurrence of convulsions is not in keeping with the results of animal experiments, studies of epileptic patients treated with ...
J G, Edwards, M, Glen-Bott
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