Results 41 to 50 of about 15,190 (293)
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
A plea for a modal realist epistemology [PDF]
, 2000 David Lewis’s genuine modal realism postulates the existence of concrete possible worlds that are spatio-temporally discontinuous with the concrete world we inhabit. How, then, can we have modal knowledge?
Bueno, O., Shalkowski, S.
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
A Surprising Closeness in Latin American Academia: Luther and Certain Neurosciences
Open Theology, 2018 The purpose of this paper is to show a surprising coincidence between Lutheran Protestantism and physicalist neurosciences regarding the negation of free will and how this issue can begin to be studied in Latin American academia.
Martínez-Barrera Jorge
doaj +1 more source
Assumptions Concerning the Social Sciences
American Journal of Islam and Society, 1993 This paper comprises three major sections. The first section discusses modem social assumptions concerning the existence of human beings and their societies. It also explains the impact of these assumptions on organizational theory.
Ebtihaj Al-A‘ali
doaj +1 more source
II—Resemblance Nominalism, Conjunctions and Truthmakers [PDF]
, 2013 The resemblance nominalist says that the truthmaker of 〈Socrates is white〉 ultimately involves only concrete particulars that resemble each other. Furthermore he also says that Socrates and Plato are the truthmakers of 〈Socrates resembles Plato〉, and ...
Rodriguez-Pereyra, Gonzalo
core
, 2017 Bare nominals (also called “bare nouns”) are nominal structures without an overt article or other determiner. The distinction between a bare noun and a noun that is part of a larger nominal structure must be made in context: Milk is a bare nominal in I bought milk, but not in I bought the milk.
Le Bruyn, B.S.W. +2 more
openaire +2 more sources
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Three ways of resisting essentialism about natural kinds [PDF]
, 2011 Essentialism about natural kinds has three tenets. The first tenet is that all and only members of a natural kind has some essential properties. The second tenet is that these essential properties play a causal role.
Nanay, Bence
core