Results 51 to 60 of about 39,340 (362)
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
E. Durkheim’s concept of sacredness
E. Durkheim’s concept of sacredness as formulated in The Elementary Forms of the Religious Life aims at explaining why and how an aggregate of people becomes ‘a single whole’ and reproduces itself.
A. E. Kapishin
doaj +1 more source
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Maribel Fernández, Murdoch Gabbay
openaire +2 more sources
Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt +5 more
wiley +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Are musical works sound structures? [PDF]
This paper is about the dilemma raised against musical ontology by Roger Scruton, in his The Aesthetics of Music: either musical ontology is about certain mind-independent “things” (sound structures) and so music is left out of the picture, or ...
Guerreiro Vitor
doaj +1 more source
A plea for a modal realist epistemology [PDF]
David Lewis’s genuine modal realism postulates the existence of concrete possible worlds that are spatio-temporally discontinuous with the concrete world we inhabit. How, then, can we have modal knowledge?
Bueno, O., Shalkowski, S.
core
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
Suárez y quienes negaron el intelecto agente en el s. XVI
Suárez and who denied the agent intellect in s. XVIIn this paper three theses on the agent intellect of various Renaissance writers are studied: a) those that deny the real distinction between one and another intellect: Jacques Lefèvre d'Étaples ...
Juan Fernando Sellés Dauder
doaj +1 more source
The possibility of onion worlds: rebutting an argument for structural universals [PDF]
The possibility of gunk has been used to argue against mereological nihilism. This paper explores two responses on the part of the microphysical mereological nihilist: (1) the contingency defence, which maintains that nihilism is true of the actual world;
Williams, J.R.G.
core +2 more sources

