Results 41 to 50 of about 39,340 (362)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

A Surprising Closeness in Latin American Academia: Luther and Certain Neurosciences

open access: yesOpen Theology, 2018
The purpose of this paper is to show a surprising coincidence between Lutheran Protestantism and physicalist neurosciences regarding the negation of free will and how this issue can begin to be studied in Latin American academia.
Martínez-Barrera Jorge
doaj   +1 more source

Assumptions Concerning the Social Sciences

open access: yesAmerican Journal of Islam and Society, 1993
This paper comprises three major sections. The first section discusses modem social assumptions concerning the existence of human beings and their societies. It also explains the impact of these assumptions on organizational theory.
Ebtihaj Al-A‘ali
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Three ways of resisting essentialism about natural kinds [PDF]

open access: yes, 2011
Essentialism about natural kinds has three tenets. The first tenet is that all and only members of a natural kind has some essential properties. The second tenet is that these essential properties play a causal role.
Nanay, Bence
core  

Internal Realism and the Reality of God [PDF]

open access: yes, 2014
How do religions refer to reality in their language and symbols, and which reality do they envisage and encounter? on the basis of some examples of an understanding of religion without reference to reality, I first answer the question of what ”realism ...
Grosshans, Hans-Peter
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

U zródeł współczesnego nominalizmu w filozofii matematyki

open access: yesZagadnienia Filozoficzne w Nauce, 2006
Nominalism is one of the most important positions in the contemporary philosophy of mathematics. The goal of this article is to point out various factors that have effected the rapid development of nominalism.
Anna Frąckowiak–Ciesielska
doaj  

Fictionalism and the problem of universals in the philosophy of mathematics [PDF]

open access: yesFilozofija i Društvo, 2018
Many long-standing problems pertaining to contemporary philosophy of mathematics can be traced back to different approaches in determining the nature of mathematical entities which have been dominated by the debate between realists and ...
Đorđević Strahinja
doaj   +1 more source

II—Resemblance Nominalism, Conjunctions and Truthmakers [PDF]

open access: yes, 2013
The resemblance nominalist says that the truthmaker of 〈Socrates is white〉 ultimately involves only concrete particulars that resemble each other. Furthermore he also says that Socrates and Plato are the truthmakers of 〈Socrates resembles Plato〉, and ...
Rodriguez-Pereyra, Gonzalo
core  

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