Results 41 to 50 of about 43,430 (308)
AbstractPlotkinʼs style of Structural Operational Semantics (SOS) has become a de facto standard in giving operational semantics to formalisms and process calculi. In many such formalisms and calculi, the concepts of names, variables and binders are essential ingredients. In this paper, we propose a formal framework for dealing with names in SOS.
Matteo Cimini +3 more
openaire +2 more sources
‘Sacrifical lambs’ or candidate mimicking?: gender-based nomination strategies in elections
This paper explores an alternative mechanism for understanding the drivers of the nomination of women for elective office in single-member electoral systems.
Lago, I +3 more
core +1 more source
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du +15 more
wiley +1 more source
A self‐supervised multi‐view graph fusion framework integrates spatial multi‐omics, excelling in domain identification and denoising. It reconstructs spatial pseudo‐expression, jointly analyzes multi‐omics data, infers RNA velocity, predicts spatial omics features from single‐cell multi‐omics, and detects spatially dark genes and transcription factors,
Yuejing Lu +8 more
wiley +1 more source
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun +19 more
wiley +1 more source
Tumor‐Infiltrating mregDCs Restrain Anti‐Tumor Immunity in Early Relapse HCC
Tumor‐infiltrating mregDCs are regulated by the TNFR2‐non‐canonical NF‐κB axis, which is mediated by TNF‐α secreted by CD161+CD8+ T cells. These mregDCs recruit CD161+CD8+ T cells via the CCL20‐CCR6 axis, forming a positive feedback loop that enhances immunosuppression, promotes early recurrence of HCC, and further confirms TNFR2 as a key therapeutic ...
Zefan Zhang +13 more
wiley +1 more source
A non‐canonical core transcriptional regulatory circuit, composed of ID3, SMAD3, and NR2F2, drives Osimertinib resistance in non‐small cell lung cancer through super‐enhancer‐mediated activation of EPAS1, which couples neuroendocrine differentiation with ferroptosis evasion.
Aochu Liu +15 more
wiley +1 more source
FUNCTIONAL AND SEMANTIC PROPERTIES OF LOANWORDS IN THE RUSSIAN LANGUAGE (BASED ON HYPERTEXTS)
The author studies functional and semantic properties of foreign-language nouns revealed in the form of the oral written language in computer-mediated communication, taking into account the debatability of issues about the borders of a loanword's notion,
Novikov Vladimir Borisovich
doaj +1 more source
Le sobriquet algérien : une pratique langagière et sociale
This article is an effort at understanding nick names or more personal pet names, a real sociocultural and universal linguistic phenomenon, particularly dynamic and prolific in all world naming systems, and especially in Algeria.On the basis of a corpus ...
Ouerdia Yermeche
doaj +1 more source

