Results 111 to 120 of about 11,770 (301)

Compositional logics of nominative data

, 2015
Logics that are oriented on program specification are proposed. These logics are constructed in a semantic-syntactic style on a basis of composition nominative approach.
Nikitchenko, M.S., Shkilniak, S.S.
core  

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

Liste nominative des souscripteurs

, 1984
Liste nominative des souscripteurs. In: Cahiers de la littérature du XVIIe siècle, n°6, 1984. Hommage à René Fromilhague. pp.

core   +1 more source

LF Intervention Effects and Nominative Objects in Japanese [PDF]

, 2014
This paper provides new data to tease apart existing analyses of the wide scope behavior of nominative objects in the Japanese potential construction.
Funakoshi, Kenshi, Takahashi, Masahiko
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KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

Advanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie, Jie Huang, Chunhao Cao, Zhenchao Tang, Xingchen Li, Jianmin Guo, Xinxin Chen, Fang Wang, Dongyi He, Jie Li, Yu Du, Bing He, Jianhua Yao, Aiping Lu, Chao Liang   +14 more
wiley   +1 more source

Os marcadores ga e wa em japonês: um estudo dos traços morfossintáticos e semânticos para a inserção vocabular [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Linguística, Florianópolis, 2009.Esta tese, assumindo a arquitetura de gramática da Morfologia Distribuída, tem por objetivo ...
Fuchs, Cristina Yukie Miyaki
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AARS1‐Mediated H3K27 Lactylation Rewires Glycolysis to Sustain Aggressive and Recurrent Bladder Cancer

Advanced Science, EarlyView.
AARS1 drives PI3K–AKT–mTOR‐dependent glycolysis in bladder cancer, promoting lactate accumulation, increased lactylation, H3K27la enrichment at the HK2 promoter, and HK2 transcription. HK2 reinforces glycolysis, sustaining a metabolic–epigenetic program associated with tumor progression, recurrence, and metastasis.
Qin Yuan, Tianbao Song, Yipeng He, Sihan Xia, Yaoqiu Huang, Wenlin He, Qin Yi, Zefeng Wang, Peihan Wang, Chenbo Huang, Linzhi Li, Zhen Yin, Fan Cheng, Weimin Yu   +13 more
wiley   +1 more source

THE STRUCTURE AND SOCIOPRAGMATICAL POTENTIAL OF NOMINATIVE ROWS IN THE CREATIVE WORKS BYV.P. ASTAFJEV AND H. BÖLL: THE COMMON AND PECULIAR FEATURES

Polylinguality and Transcultural Practices, 2016
The problem of functioning of characters’ nominative rows in literary works within modern scientific paradigm is characterized by fractional theoretical description and the necessity of new applied approaches in the presentation and description of the ...
O V Sheverinova
doaj  

The nominative case: its form and functions

, 2008
Functions of the nominative in sentences (subject, agens, topic, vocative), nominative in the single-element nominal ...
Vondráček, Miloslav
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