Results 141 to 150 of about 90,463 (317)

Machine learning‐driven investigation on liquid–liquid phase separation‐related prognostic signature in diffuse large B‐cell lymphoma

open access: yesBritish Journal of Haematology, EarlyView.
Summary Diffuse large B‐cell lymphoma (DLBCL) is the most common aggressive non‐Hodgkin lymphoma and is characterized by substantial heterogeneity. This study aimed to develop a liquid–liquid phase separation (LLPS)‐related prognostic model to improve risk stratification.
Zhen‐Zhong Zhou   +11 more
wiley   +1 more source

Reducing complexity in International Bladder Cancer Group intermediate‐risk non‐muscle‐invasive bladder cancer stratification: a three‐factor approach

open access: yesBJU International, EarlyView.
Objectives To evaluate whether a simplified risk model preserves the prognostic performance of the International Bladder Cancer Group (IBCG) five‐factor risk stratification model in intermediate‐risk (IR) non‐muscle‐invasive bladder cancer (NMIBC). Patients and Methods We performed a multicentre retrospective analysis of 2822 patients with IR NMIBC ...
Jayant Siva   +12 more
wiley   +1 more source

Guideline of guidelines: pelvic lymph node dissection at time of radical prostatectomy

open access: yesBJU International, EarlyView.
Objective To provide a comprehensive review, analysis and critique of guidelines from various oncological and urological organisations regarding the use pelvic lymph node dissection (PLND) in men undergoing radical prostatectomy (RP) for primary treatment of prostate cancer (PCa).
Jonathon Carll   +8 more
wiley   +1 more source

Outperforming Traditional Staging: A Novel Nomogram for HR-Positive Breast Cancer

open access: yes
Chaoxing Liu,1– 3,* Jiabin Ding,1– 3,* Jinbiao Xu,1– 3,* Chen Fang,1– 3 GuoHua Zhang,2 Chao Shi,1,3 Feng Qiu1,3 1Department of Oncology, Gaoxin Branch of the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People’s ...
Zhang G   +6 more
core  

T Cell Heterogeneity Shaped by Alternative Splicing Predicts Prognosis in Hepatocellular Carcinoma

open access: yesCancer Science, EarlyView.
T cell‐specific alternative splicing events shape T cell heterogeneity in HCC. Single‐cell analysis identified two splicing‐defined T cell subpopulations with distinct functional profiles. Subpopulation‐associated splicing events were used to construct a prognostic model predicting patient survival.
Xiaohui Peng   +11 more
wiley   +1 more source

Epithelial YPEL3 Modulates CD8+ T‐Cell Infiltration and Tumor Progression Through CREB1–CXCL16 Signaling in HNSCC

open access: yesCancer Science, EarlyView.
YPEL3 functions as a tumor suppressor in HNSCC by inhibiting tumor progression and promoting apoptosis. Mechanistically, it enhances epithelial–immune crosstalk through the CREB1‐mediated CXCL16–CXCR6 axis, facilitating CD8+ T‐cell infiltration and highlighting its potential as a prognostic biomarker and immunotherapy target.
Yalun Li   +7 more
wiley   +1 more source

Machine Learning-Based Nomogram for Predicting Overall Survival in Elderly Patients with Cirrhotic Hepatocellular Carcinoma Undergoing Ablation Therapy

open access: yes
Wenying Qiao,1– 5,* Shugui Sheng,1– 3,* Junnan Li,1– 3,* Ronghua Jin,1– 4 Caixia Hu5 1Beijing Key Laboratory of Emerging Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Beijing ...
Qiao W, Hu C, Li J, Jin R, Sheng S
core  

Femtosecond Laser Created Corneal Allogenic Intrastromal Ring Segments for Keratoconus

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To evaluate the clinical outcomes of femtosecond laser‐created corneal allogenic intrastromal ring segments (femto‐CAIRS) in keratoconic eyes using a newly described nomogram. Methods This retrospective case series recruited 85 eyes from 75 patients.
David J. Gunn   +2 more
wiley   +1 more source

Prognostic Factors and Nomogram for Klebsiella pneumoniae Infections in Intensive Care Unit

open access: yes
Chunjing Du,1,2,* Hua Zhang,3,* Yi Zhang,1,4,* Hanwen Zhang,1,4 Jiajia Zheng,5 Chao Liu,6 Fengmin Lu,7 Ning Shen1,6 1Department of Pulmonary and Critical Care Medicine, Peking University Third Hospital, Beijing, 100191, People’s Republic of ...
Zheng J   +6 more
core  

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