Results 161 to 170 of about 120,426 (297)

Clinical implications of PD‐L1 expression in oncogene‐driven NSCLC: Differential responses to targeted agents and immune checkpoint inhibitors

open access: yesInternational Journal of Cancer, Volume 159, Issue 1, Page 269-279, 1 July 2026.
What's New? PD‐L1 is a reliable biomarker for predicting immunotherapy efficacy in patients with non‐small‐cell lung cancer lacking oncogenic driver mutations. However, its significance in patients with driver mutations remains unclear. In this study of 273 patients with stage IV non–‐small‐cell lung cancer harboring diverse driver alterations and PD ...
Xiaoxiao Fan   +7 more
wiley   +1 more source

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

open access: yesInternational Journal of Cancer, Volume 159, Issue 1, Page 11-29, 1 July 2026.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang   +5 more
wiley   +1 more source

Metabolic‐immune interactions in gastric cancer T cells: A single‐cell atlas for prognostic biomarker identification

open access: yesQuantitative Biology, Volume 14, Issue 2, June 2026.
Abstract Metabolic alterations and immune dysfunction within the gastric tumor microenvironment critically drive gastric cancer (GC) progression and therapeutic resistance. Although single‐cell RNA sequencing (scRNA‐seq) has unveiled cellular heterogeneity in GC, the metabolic landscapes of tumor cells and their interplay with immune components remain ...
Junjun Liu   +7 more
wiley   +1 more source

Estimation for a Simple Exponential Model [PDF]

open access: yes
Methods of parameter estimation for exponential model arising in epidemiological studies and biological ...
Cornell, R. G., Speckman, J. A.
core   +1 more source

Preoperative Prediction of Microvascular Invasion in Hepatocellular Carcinoma: A Chinese Retrospective Multicenter Study Based on Global Meta‐Analysis

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Objective Microvascular invasion (MVI) has been identified as a risk factor for the prognosis of patients with hepatocellular carcinoma (HCC). However, it can only be diagnosed pathologically, and thus no widely applicable preoperative MVI risk prediction model has been established.
Jia Xu   +10 more
wiley   +1 more source

A Novel Nomogram Incorporating the Aggregate Index of Systemic Inflammation, Clinicopathological Parameters and Molecular Classification to Predict Recurrence of Endometrial Cancer: A Multi‐Center Retrospective Study

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT This study evaluated the aggregate index of systemic inflammation (AISI) for predicting postoperative recurrence in endometrial cancer (EC). A total of 1557 patients were enrolled and divided into training (n = 1030) and validation (n = 527) cohorts. The optimal AISI cutoff was determined by ROC curve analysis.
Chenfan Tian   +6 more
wiley   +1 more source

Predicting Prognosis for Gastric Cancer Patients Receiving Neoadjuvant Treatment With Body Composition‐Based Deep Learning

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background This study sought to develop an innovative body composition (BC)‐based deep learning (DL) model to precisely evaluate survival in gastric cancer (GC) patients undergoing neoadjuvant treatment (NT). Materials and Methods This retrospective study included GC patients undergoing NT from two centers.
Yingjing Zhang   +6 more
wiley   +1 more source

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