Results 171 to 180 of about 106,048 (268)

Accuracy of surrogate outcomes in predicting true endpoints of surgical periodontal therapy. A narrative review with a 20‐year longitudinal analysis

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Periodontal clinical trials commonly use surrogate end points (e.g., probing pocket depth [PPD], clinical attachment level [CAL], bleeding on probing [BoP], and composite scores such as the Periodontal Risk Score [PRS]) for efficiency, yet tooth loss, treatment burden/cost, and re‐treatment are the definitive patient‐relevant ...
Muhammad H. A. Saleh   +7 more
wiley   +1 more source

Prolonged rod photoresponse and enhanced cone sensitivity in the transgenic mouse retina lacking arrestin and guanylate cyclase activating proteins

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Analyses from mutant mouse retinal explants gives invaluable insights of the photosignaling process in rod and cone photoreceptor cells. A, Illustration of retinal photovoltage recordings. A retinal explant (pink) is placed in a transparent device which has electrodes to monitor transretinal voltage (red and blue circles).
Shinya Sato   +3 more
wiley   +1 more source

Prediction Models for Delayed Bleeding After Colorectal Endoscopic Submucosal Dissection: A Systematic Review and Critical Appraisal

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Background Although many predictive models have been developed or validated for delayed bleeding after colorectal endoscopic submucosal dissection (ESD), their methodological quality and clinical utility remain uncertain. We systematically reviewed and critically appraised all available predictive models for this outcome.
Da Miao, Zhuoer Hou, Yao Ge, Haiou Qi
wiley   +1 more source

External Validation of the ARCAD Nomogram in a Real-World Cohort with Stage 4 Colorectal Cancer. [PDF]

open access: yesCancers (Basel)
Yu J   +8 more
europepmc   +1 more source

Prevention and treatment of post‐endoscopic retrograde cholangiopancreatography cholangitis: Current evidence and future directions

open access: yesClinical and Translational Discovery, Volume 6, Issue 6, December 2026.
1. Prevention strategies should be stratified by preoperative cholangitis status. 2. For pre‐existing cholangitis, therapeutic antibiotics plus urgent drainage are essential; ENBD and stents show similar efficacy. 3. Early biliary drainage is the cornerstone of treatment; endoscopic drainage is preferred, with PTCD/EUS‐BD as second‐line. 4.
Hao‐Xin Chen, Jun Yao
wiley   +1 more source

Computed Tomography‐Based Morphometric Analysis Reveals Intercondylar Notch Stenosis and Osteophytes Are Associated With Anterior Cruciate Ligament Injury

open access: yesArthroscopy, Volume 42, Issue 11, Page 2646-2658, November 2026.
Purpose To quantitatively assess intercondylar notch morphometrics using 3‐dimensional computed tomography reconstruction, evaluate their association with anterior cruciate ligament (ACL) injury in Asian populations, and investigate the prevalence of osteophytes in patients with ACL injury.
Xiaozhong Ma   +9 more
wiley   +1 more source

Neoadjuvant Therapy for Non‐Small Cell Lung Cancer: Recent Advances and Future Directions

open access: yesCancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Neoadjuvant therapy has become an integral component of the multidisciplinary management of resectable non–small cell lung cancer (NSCLC). The introduction of immune checkpoint inhibitors (ICIs) has transformed the perioperative treatment landscape by improving pathological response rates, reducing the risk of recurrence, and offering the ...
Hao An   +15 more
wiley   +1 more source

Machine Learning-Based Nomogram for Predicting Overall Survival in Elderly Patients with Cirrhotic Hepatocellular Carcinoma Undergoing Ablation Therapy

open access: yes
Wenying Qiao,1– 5,* Shugui Sheng,1– 3,* Junnan Li,1– 3,* Ronghua Jin,1– 4 Caixia Hu5 1Beijing Key Laboratory of Emerging Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Beijing ...
Qiao W, Hu C, Li J, Jin R, Sheng S
core  

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