Results 271 to 280 of about 130,883 (345)

Dual‐center prospective validation of an early second‐trimester predictive model integrating BMI trajectories and pathophysiological biomarkers for gestational diabetes risk stratification

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 1, Page 150-164, January 2026.
This dual‐center study of 1,450 women developed an early GDM prediction model (AUC≈0.685) using routine first‐trimester clinical data. With an NPV >82 %, it enables effective risk stratification for targeted screening. ABSTRACT Objective To develop and validate an early second‐trimester predictive model integrating body mass index (BMI) trajectories ...
Junxiang Gao   +17 more
wiley   +1 more source

The JAK2V617F and CALR mutations and risk of cancer, cardiovascular diseases, and all‐cause mortality

open access: yesJournal of Internal Medicine, Volume 299, Issue 1, Page 79-94, January 2026.
Abstract Background Clonal hematopoiesis (CH) is associated with adverse outcomes. We hypothesized that CH (JAK2V617F and CALR) is associated with cancer, vascular disease, and all‐cause mortality, even at a variant allele frequency (VAF) <1%. Methods We screened 19,832 individuals from the Danish General Suburban Population Study for JAK2V617F and ...
Morten Kranker Larsen   +17 more
wiley   +1 more source

Construction of a Platelet‐Related Gene Signature for Predicting Prognosis and Drug Sensitivity in Colorectal Cancer

open access: yesEuropean Journal of Cancer Care, Volume 2026, Issue 1, 2026.
Background Colorectal cancer (CRC) ranks among the most prevalent forms of cancer and is a significant contributor to cancer‐related mortality globally. Platelets play a crucial role in tumor biology by interacting with various immune cells, influencing multiple biological processes.
Yufang Wang   +4 more
wiley   +1 more source

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