Results 91 to 100 of about 10,193 (191)

Novel BRAF fusion in Erdheim–Chester disease with pulmonary manifestations: Importance of RNA‐based testing and response to MEK inhibition

Histopathology, EarlyView.
Igor Odintsov, Henry D. Tazelaar, Jerry C. Lee, Lloyd E. Damon, Walter Patrick Devine, Kirk D. Jones   +5 more
wiley   +1 more source

Efficacy of MAPK inhibitors in children with neurodegenerative Langerhans cell histiocytosis: Results from the European Consortium for Histiocytosis

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract Neurodegenerative Langerhans cell histiocytosis (ND‐LCH) is a severe and debilitating complication of LCH with no effective treatment. In this study, we assessed the efficacy of MAPK inhibitors (MAPKi) in a large cohort of children with ND‐LCH. We included pediatric patients with ND‐LCH who received MAPKi between 2013 and 2025.
Francesco Pegoraro, Francois Chalard, Dmitry Evseev, Mohamed Barkaoui, Solenne Le Louet, Julian Thalhammer, Nathalie Aladjidi, Alexandra Salmon, Perrine Marec‐Berard, Stefania Gaspari, Carmela De Fusco, Irene Trambusti, Antonio Verrico, Anna Raciborska, Karel Svojgr, Zdenka Křenová, Olga Slater, Gerard Millen, Myriam Ben Arush, Dana Ashkenazi Lustig, Tatiana Von Bahr Greenwood, Caroline Hutter, Itziar Astigarraga, Mónica López‐Duarte, Lorena Valero‐Arrese, María José Ortega Acosta, Cor van den Bos, Leonie Naeije, Daniel Martin‐Munoz, Anna Perrone, Marzia Mortilla, Olivier Felician, Ahmed Idbaih, Sébastien Héritier, Vasanta Nanduri, Milen Minkov, Jan‐Inge Henter, Elena Sieni, Jean Donadieu   +38 more
wiley   +1 more source

Multiple cutaneous reticulohistiocytoma

Indian Journal of Dermatology, 2016
Multicentric reticulohistiocytosis is a rare non-Langerhans cell histiocytosis characterized in its full form by severe destructive arthritis, cutaneous nodules, and systemic manifestations.
Karishma D Hemmady, Shylaja S Someshwar, Hemangi R Jerajani   +2 more
doaj   +1 more source

Multifocal Langerhans Cell Histiocytosis in an Adult

, 2017
Eosinophilic granuloma (EG) is the most common and benign form of the spectrum of disorders referred to as Langerhans cell histiocytosis (LCH). Langerhans cell histiocytosis is primarily regarded as a pediatric disease, with few adult cases of multifocal
Nielsen, Natalie, Most, Mathew J., Sirkis, Hartley M., Akalin, Ali   +3 more
core  

A Case of Multisystemic Langerhans Cell Histiocytosis in an Adult

, 2011
Langerhans cell histiocytosis is a rare disease in adults with a myriad of clinical presentations. A case of multisystemic Langerhans cell histiocytosis with involvement of bone, skin, lungs, and the hypothalamic-pituitary-axis is reported.
Chiaw Ling Chng MBBS, MRCP
core   +1 more source

Juvenile Xanthogranuloma: Case Report and Literature Review

International Medical Case Reports Journal, 2020
Sadegh Vahabi-Amlashi, Masoumeh Hoseininezhad, Zahra Tafazzoli Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, IranCorrespondence: Zahra TafazzoliDepartment of Dermatology, Imam Reza Hospital, Ibn e Sina Street ...
Vahabi-Amlashi S, Hoseininezhad M, Tafazzoli Z   +2 more
doaj  

Langerhans Cell Histiocytosis Diagnosed In An Elderly Patient [histiocitose De Células De Langerhans Diagnosticada Em Um Paciente De Idade Avançada] [PDF]

, 2015
Langerhans cell histiocytosis is a rare disease characterized by proliferation of Langerhans cells. We report a case of Langerhans cell histiocytosis in a 63-year-old patient, who presented an expansile periorbital lesion as the first symptom, in whom ...
de Carvalho K.M., Iyeyasu J.N., Altemani J., Vaz A.C.M., Queiroz L.S., Reis F.   +5 more
core   +1 more source

Novel actionable ROS1::GIT2 fusion in non-Langerhans cell histiocytosis with central nervous system involvement. [PDF]

Acta Neuropathol, 2023
Bedics G, Csóka M, Reiniger L, Varga E, Liptai Z, Papp G, Bekő A, Cervi C, Bödör C, Scheich B.   +9 more
europepmc   +1 more source

Langerhans cell histiocytosis: a diagnostic dilemma

, 2012
Langerhans cell histiocytosis (LCH) is a rare clonal neoplastic disorder of unknown aetiology which can present with a diverse range of clinical presentations.
Paul L Ryan, Piper, Kim M, Francis J Hughes, Hughes, Francis J; id_orcid, Ryan, Paul L, Kim M Piper   +5 more
core   +1 more source

Cutaneous Langerhans Cell Histiocytosis

, 2008
We report a 4-year-old boy with localized Langerhans cell histiocytosis. The lesions were restricted to the skin of his back, eyelids, glans penis and prepuce for 2 years. Histopathological and electron microscopic examinations showed typical features of
吳亮遠;蔡呈芳;陳佑甫;洪志明, WU, LIANG-YUANNG;TSAI, TSEN-FANG;CHEN, YU-FU;HUNG, CHIN-MING;WU, CHIEH-JEN   +1 more
core