Results 41 to 50 of about 14,204,415 (185)

Juvenile xanthogranuloma of the cerebellopontine angle: A case report and review of the literature

Otolaryngology Case Reports, 2019
Juvenile xanthogranuloma (JXG) is a non-Langerhans cell histiocytosis, most often presenting with skin lesions of the head, neck, and upper trunk. Intracranial presentations have been previously described, however, due to its rarity, treatment algorithms
Sarah M. Tittman, Ashley M. Nassiri, Nauman F. Manzoor, Robert J. Yawn, Bret C. Mobley, John C. Wellons, III, Alejandro Rivas   +6 more
doaj   +1 more source

Cutaneous Rosai‐Dorfman Disease With MAP2K1 Mutation Treated With Encorafenib and Binimetinib

JEADV Clinical Practice, EarlyView.
ABSTRACT Rosai‐Dorfman disease (RDD) is a rare histiocytic disorder with unifocal to multisystemic involvement. Activating mutations in the MAPK/ERK pathway can occur in up to 50% of RDD cases. We report a case of cutaneous RDD (C‐RDD) with facial and truncal lesions harboring an activating MAP2K1 (MEK1) mutation that showed a complete response to a ...
Melike Ak, Reinhard Dummer, Egle Ramelyte   +2 more
wiley   +1 more source

Solving a Mystery . . . 8 Years Later

Journal of Investigative Medicine High Impact Case Reports, 2018
Erdheim-Chester disease is a rare non-Langerhans cell histiocytosis with multisystem involvement and insidious symptoms. In this article, we describe an interesting case of Erdheim-Chester disease that was eventually diagnosed 8 years after symptoms ...
Hayan Jouni MD, Ronald S. Kuzo MD, Nandan S. Anavekar MBBCh   +2 more
doaj   +1 more source

Multicentric reticulohistiocytosis: a case report

BMC Research Notes, 2018
Background Multicentric reticulohistiocytosis is a rare form of non-langerhans cell histiocytosis presenting with skin changes and erosive arthritis. Infiltration of histiocytes and multinucleated giant cells are typical histological findings and confirm
Azadèh Farokhi, Richard M. van Vugt, Rick Hoekzema, Michael T. Nurmohamed   +3 more
doaj   +1 more source

Eosinophilic Granuloma: A Rare and Often Benign Condition Presenting as a Lump on the Head, which was Easily Treated

European Journal of Case Reports in Internal Medicine, 2021
Eosinophilic granuloma is a localized, non-invasive form of Langerhans cell histiocytosis. It usually develops in the long bones and is more frequent in children under the age of 10 years. It is very rare in adults.
Tatiana Pires, Catarina Duarte Santos, Miguel Gonzalez Santos, Luís Luz, Ana Ferrão, Maria J. Banza   +5 more
doaj   +1 more source

Extraintestinal Manifestation of Crohn's Disease in the Middle Ear—A Case Report

The Laryngoscope, EarlyView.
A unique clinical case with extraintestinal manifestation of Crohn's disease in the middle ear, causing severe inflammation and troublesome symptoms. The combination of systemic therapy and surgery curbed the middle ear manifestation upon diagnosis.
Julia Arebro
wiley   +1 more source

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

Indeterminate Cell Histiocytosis: Report of a Case

Acta Medica Iranica, 2014
Indeterminate cell histiocytosis is a very rare disorder of histiocytes proliferation. It has both Langerhans and non-Langerhans cell histiocytosis immunophenotypic features.
Alireza Ghanadan, Kambiz Kamyab, Mazaher Ramezani, Azadeh Goodarzi, Maryam Daneshpajouh, Kamran Balighi, Mahsa Ansari, Seyyed Farzad Mirfallah Nassiri, Soroush Daklan   +8 more
doaj  

Pregnancy in CTD‐interstitial lung disease: Current evidence, clinical challenges, and a proposed management algorithm

Rheumatology &Autoimmunity, EarlyView.
Summary of pregnancy management in CTD‐ILD across preconception, antenatal, and postpartum phases, emphasizing risk stratification and multidisciplinary care. 6MWT, 6‐min walk test; CTD‐ILD: connective tissue disease‐interstitial lung disease; DLCO, diffusion capacity of the lung for carbon monoxide; FVC, forced vital capacity; MDT, multidisciplinary ...
Khaled Aldhuaina, Ghaydaa Aldabie, Mohammad Abdulsalam, Ali Jawad   +3 more
wiley   +1 more source

Extraosseous langerhans cell histiocytosis in children

, 2008
Langerhans cell histiocytosis, a rare disease that occurs mainly in children, may produce a broad range of manifestations, from a single osseous lesion to multiple lesions involving more than one organ or system.
Letovanec, I., Geoffray, A., Letovanec, Igor, Waibel, Peter, Georg Eich, Peter Waibel, Schmidt, S., Gudinchet, Francois, Hanquinet, Sylviane, Eich, Georg, Anne Geoffray, Wolf, R., Rainer Wolf, Sabine Schmidt, Geoffray, Anne, Hanquinet, S., Schmidt, Sabine, Alamo-Maestre, L., Francois Gudinchet, Alamo-Maestre, Leonore, Eich, G., Gudinchet, F., Igor Letovanec, Leonore Alamo-Maestre, Waibel, P., Wolf, Rainer, Sylviane Hanquinet   +26 more
core   +1 more source